TitleAntibodies against equine herpesvirus 1 in the cerebrospinal fluid in the horse.
Publication TypeJournal Article
Year of Publication1985
AuthorsBlythe, LL, Mattson, DE, Lassen, ED, Craig, AM
JournalThe Canadian veterinary journal. La revue vétérinaire canadienne
Date Published1985 Jul

Neutralizing antibodies against equine herpesvirus 1 were measured in serum and cerebrospinal fluid of 16 horses and ponies from a closed herd both before and after vaccination with modified live equine herpesvirus 1. These titers were also measured in 22 neurologically normal and 15 neurologically abnormal horses at a teaching hospital. Animals from the closed herd had prevaccination serum titers up to 1:8 and postvaccination serum titers up to 1:128. Horses from the teaching hospital had serum titers up to 1:64. Cerebrospinal fluid titers were not detected in the vaccinated horses or the neurologically normal horses but a low titer (1:8) was noted in one neurologically abnormal horse. This titer probably resulted from hemorrhage into the cerebrospinal fluid following trauma.