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Cryptococcal Antigen Detection - Panel
|Test Name:||Diagnostic Section:||Fee:|
|Cryptococcal Antigen Detection - Panel
|Species:||Set up days:||Turn Around Time:|
|All Species (exc. primates)
||M, Tu, W, Th, F||1 day
|Sterile non-hemolysed serum or CSF; 1.0 ml preferred, 0.5 ml minimum
|Collect in red top tube, separate serum promptly or collect in serum separator tube, spin and send "as-is".
|Refrigerated, in leak proof tubes (s). Overnight or 2-day shipping is recommended.
The Cryptococcus Antigen Panel is a two test combination. Testing should be done when clinical evidence suggests diagnosis of cryptococcal disease and not as a screening procedure for the general population.
The first test is a lateral flow assay which yields a presence/absence report for detection of the capsular polysaccharide antigens of Cryptococcus species complex (Cryptococcus neoformans, serotype A and D, and Cryptococcus gatti, serotype B and C). It does not provide a quanitative titer of the antigen concentration. If this test is positive, it is followed by a latex agglutination titer to obtain a semi-quantitative titer of the cryptococcal antigen in the blood or CSF.
If the initial qualitative test is negative for the capsular polysaccharide antigen, the second titration will not be run.