Stuart C. Helfand

Dr. Stuart Helfand
E-Mail: 
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Professor
Oncology
Small Animal Internal Medicine

268 Magruder Hall
541-737-4812 (hospital reception)
541-737-4818 (fax)
Stuart.Helfand@oregonstate.edu

Professional and Research Interests: 

My laboratory has a long standing interest in cancer immunotherapy and its impact on modulation of angiogenesis. We have been particularly interested in development of novel approaches to target the immunostimulatory and anti-angiogenic cytokine, interleukin-12, to vasculature within the tumor microenvironment. This work has evolved to include other approaches to suppress endothelial cell proliferation. Our current focus is on tyrosine kinase signaling pathways in malignant endothelial cells (i.e., canine hemangiosarcoma) in an effort to elucidate derangements and identify candidate aberrant kinases amenable to blockade by tyrosine kinase inhibitors. Other areas of interest include development of novel therapeutics for canine osteosarcoma.

Oregon Cancer Care for Animals (ORCCA)

Selected Publications: 

Helfand SC: Canine hemangiosarcoma: A tumor of contemporary interest. Cancer Therapy. 6B:457-462, 2008

Publications

2013
2009
2007
2006
2005
2004