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Beth A. Valentine
142 Magruder Hall
541-737-5061 (voice mail)
- Alpha Chapter, The Society of Phi Zeta
- Phi Eta - CW Post College
- Pfizer Award for Research Excellence, Oregon State University, 2006
Professional and Research Interests:
- Pathology of equine disease
- Pathology of neuromuscular disease in animals
- Effect of nutrition in horses with polysaccharide storage myopathy
- Altered metabolism in horses with polysaccharide storage myopathy
I am a veterinary anatomic pathologist, in the Veterinary Diagnostic Laboratory, involved with many different species and pathologic disorders. This includes neoplasia in camelids and in horses, and non-neoplastic nodular skin disease in horses. I have a special interest in equine disease and in neuromuscular disease. I am currently involved in the diagnosis of equine polysaccharide storage myopathy by examination of muscle biopsy samples, and in studies involving the pathogenesis of abnormal polysaccharide storage in skeletal muscle..
Equine polysaccharide storage myopathy has been shown to be the major cause of a common muscle disorder of horses, known as exertional rhabdomyolysis or "tying up." Many other clinical manifestations, all related to abnormal muscle function, can also occur. The exact pathogenesis of equine polysaccharide storage myopathy is still not known, although pathologic findings of abnormal polysaccharide storage and response to diet change suggest abnormal metabolism of starch and sugar.
Datta K, Bartlett KH, Baer R, Byrnes E, Galanis E, Hetman J, Hoang L, Leslie MJ, MacDougall L, Magill SS, Morshed MG, Marr KA; Cryptococcus gattii Working Group of the Pacific Northwest (includes Valentine BA). Spread of Cryptococcus gattii into Pacific Northwest region of the United States. Emerg Infect Dis 15:1185-91, 2009
Sukon P, Timm KI, Valentine BA*. Esophageal anatomy of the Llama (Lama glama). Int J Morphol 27(3):811-817, 2009
Valentine BA, Divers TJ, Murphy D, Todhunter PG. Tutorial Article. Muscle biopsy diagnosis of equine motor neuron disease and equine polysaccharide storage myopathy. Equine Vet Educ 1998, 10:42-50.
Cope RB, Stang BV, Valentine BA, Bermudez LE. 2004. Topical exposure to exogenous ultraviolet-irradiated urocanic acid enhances Mycobacterium ulcerans infection in a Crl:IAF(HA)-hrBR hairless guinea-pig model of Buruli ulcer disease.. Photodermatology, photoimmunology & photomedicine. 20(1):14-20.
Valentine BA, Habecker PL, Patterson JS, Njaa BL, Shapiro J, Holshuh HJ, Bildfell RJ, Bird KE. 2001. Incidence of polysaccharide storage myopathy in draft horse-related breeds: a necropsy study of 37 horses and a mule.. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 13(1):63-8.