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214 Dryden Hall
Education and Professional Training:
- 1999: PhD. University of Illinois at Urbana-Champaign
- 1989: MS. Nanjing Agricultural University, Department of Microbiology
- American Society for Virology (Full membership)
- American Association for the Advancement of Science
- Phi Zeta-honorary Society of Veterinary Medicine
- Gamma Sigma Delta-honorary Society of Agriculture, Illinois
- 2010: New Investigator Awards
Professional and Research Interests:
- Pathogenesis of herpes virus infected animal disease
- Host and virus interaction in central nervous system
- Mechanism of herpes virus latency-reactivation cycles
- Anti-viral drug development
- New emerging viral diseases
- Viral disease diagnosis
Jin L, Perng GC, Mott KR, Osorio N, Naito J, Brick D, Carpenter D, Jones C, Wechsler SL. 2004. Replacement of LAT by the well characterized anti-apoptosis gene, cpIAP, results in a high wild type HSV-1 reactivation phenotype. Manuscript
Henderson G, Peng W, Jin L, Perng GC, Nesburn AB, Wechsler SL, Jones C. Regulation of caspase 8- and caspase 9-induced apoptosis by the herpes simplex virus type 1 latency-associated transcript. J Neurovirol. 2002;8(Suppl 2):103-11.
Jin L. 1999. Pseudorabies Virus latency associated transcript gene: Expression and Regulation, and role in the establishment of latency in swine. Jin, UMI, Ann Arbor.
Weigel RM, Scherba G, Wiemers J, Siegel AM, Austin CC, Jin L, Bowman L, Johnston NA. 1997. Application of quantitative methods and molecular biological techniques to investigation of the spread of Aujeszky's disease virus. Epidemiologie et Sante Animale 31-31: 12.17.1-12.17.2.
Jin L, Schnitzlein WM, Scherba G. 1995. Establishment of latency in the natural host animal by Aujeszky's disease (pseudorabies) virus lacking the putative LAT gene promoter. In: Advances in Swine in Biomedical Research, Vol. 1, M.E. Tumbleson and L.B. Shock (eds), Plenum Publishing, NY. pp395-408.
Moerdyk-Schauwecker M, Eide K, Bildfell RJ, Baker RJ, Black W, Graham D, Thompson K, Crawshaw G, Rohrmann GF, Jin L. 2009. Characterization of Cervidpoxvirus isolates from Oregon, California, and eastern Canada.. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 21(4):487-92.
Jin L, Carpenter D, Moerdyk-Schauwecker M, Vanarsdall AL, Osorio N, Hsiang C, Jones C, Wechsler SL. 2008. Cellular FLIP can substitute for the herpes simplex virus type 1 latency-associated transcript gene to support a wild-type virus reactivation phenotype in mice.. Journal of neurovirology. 14(5):389-400.
Carpenter D, Singh S, Osorio N, Hsiang C, Jiang X, Jin L, Jones C, Wechsler SL. 2008. A speculated ribozyme site in the herpes simplex virus type 1 latency-associated transcript gene is not essential for a wild-type reactivation phenotype.. Journal of neurovirology. 14(6):558-62.
Carpenter D, Hsiang C, Brown DJ, Jin L, Osorio N, BenMohamed L, Jones C, Wechsler SL. 2007. Stable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosis.. Virology. 369(1):12-8.
Jin L, Perng G-C, Carpenter D, Mott KR, Osorio N, Naito J, Brick DJ, Jones C, Wechsler SL. 2007. Reactivation phenotype in rabbits of a herpes simplex virus type 1 mutant containing an unrelated antiapoptosis gene in place of latency-associated transcript.. Journal of neurovirology. 13(1):78-84.
Chan D, Cohen J, Naito J, Mott KR, Osorio N, Jin L, Fraser NW, Jones C, Wechsler SL, Perng GC. 2006. A mutant deleted for most of the herpes simplex virus type 1 (HSV-1) UOL gene does not affect the spontaneous reactivation phenotype in rabbits.. Journal of neurovirology. 12(1):5-16.
Jin L, Perng G-C, Mott KR, Osorio N, Naito J, Brick DJ, Carpenter D, Jones C, Wechsler SL. 2005. A herpes simplex virus type 1 mutant expressing a baculovirus inhibitor of apoptosis gene in place of latency-associated transcript has a wild-type reactivation phenotype in the mouse.. Journal of virology. 79(19):12286-95.