Antiepithelial autoantibodies associated with the feline eosinophilic granuloma complex.

TitleAntiepithelial autoantibodies associated with the feline eosinophilic granuloma complex.
Publication TypeJournal Article
Year of Publication1985
AuthorsGelberg HB, Lewis RM, Felsburg PJ, Smith CA
JournalAmerican journal of veterinary research
Volume46
Issue1
Pagination263-5
Date Published1985 Jan
ISSN0002-9645
KeywordsAnimals, Autoantibodies, Cat Diseases, Cats, Eosinophilic Granuloma, Epithelium, Fluorescent Antibody Technique
Abstract

A retrospective study of banked sera from 19 cats with the eosinophilic granuloma complex revealed that 68% of affected cats had circulating antibodies to components of normal cat epithelium. Seemingly, the eosinophilic granuloma complex of cats may be an autoimmune disease; however, epidermal damage caused by the eosinophilic granuloma complex may release altered self-antigens to which the cat's immune system responds.

Alternate JournalAm. J. Vet. Res.