Cellular and molecular mechanisms of internalization of mycobacteria by host cells.

TitleCellular and molecular mechanisms of internalization of mycobacteria by host cells.
Publication TypeJournal Article
Year of Publication2001
AuthorsBermudez LE, Sangari FJ
JournalMicrobes and infection / Institut Pasteur
Volume3
Issue1
Pagination37-42
Date Published2001 Jan
ISSN1286-4579
KeywordsAnimals, Epithelial Cells, Humans, Intestinal Mucosa, Macrophages, Mucous Membrane, Mycobacterium, Phagocytes, Respiratory Mucosa, Schwann Cells
Abstract

Mycobacteria are intracellular pathogens capable of invading mononuclear phagocytes, mucosal epithelial cells (including M cells) and Schwann cells. To enter cells, mycobacteria have been shown to interact with several molecules on macrophage and epithelial cell surfaces. This suggests adaptation to the host environment. In this review we address the strategies used by pathogenic mycobacteria to gain access to the intracellular environment.

Alternate JournalMicrobes Infect.