Chlamydia trachomatis IncA is localized to the inclusion membrane and is recognized by antisera from infected humans and primates.

TitleChlamydia trachomatis IncA is localized to the inclusion membrane and is recognized by antisera from infected humans and primates.
Publication TypeJournal Article
Year of Publication1998
AuthorsBannantine JP, Stamm WE, Suchland RJ, Rockey DD
JournalInfection and immunity
Volume66
Issue12
Pagination6017-21
Date Published1998 Dec
ISSN0019-9567
KeywordsAnimals, Antibodies, Bacterial, Bacterial Proteins, Cell Compartmentation, Chlamydia Infections, Chlamydia trachomatis, Chlamydophila psittaci, Humans, Macaca fascicularis, Membrane Proteins, Phosphoproteins, Sequence Homology, Amino Acid, Species Specificity
Abstract

Chlamydia psittaci produces a collection of proteins, termed IncA, IncB, and IncC, that are localized to the chlamydial inclusion membrane. In this report we demonstrate that IncA is also produced by Chlamydia trachomatis. C. trachomatis IncA is structurally similar to C. psittaci IncA and is also localized to the inclusion membrane. Immunoblot analysis demonstrated that sera from C. trachomatis-infected patients and from experimentally infected monkeys both recognized C. trachomatis IncA.

Alternate JournalInfect. Immun.