Chlamydial antigens colocalize within IncA-laden fibers extending from the inclusion membrane into the host cytosol.

TitleChlamydial antigens colocalize within IncA-laden fibers extending from the inclusion membrane into the host cytosol.
Publication TypeJournal Article
Year of Publication2002
AuthorsBrown WJ, Skeiky YAW, Probst P, Rockey DD
JournalInfection and immunity
Volume70
Issue10
Pagination5860-4
Date Published2002 Oct
ISSN0019-9567
KeywordsAntigens, Bacterial, Bacterial Proteins, Cell Division, Chlamydia, Chlamydia Infections, Chlamydia trachomatis, Chlamydophila pneumoniae, Chlamydophila psittaci, Hela Cells, Humans, Inclusion Bodies, Microscopy, Fluorescence, Phosphoproteins
Abstract

Chlamydial IncA localizes to the inclusion membrane and to vesicular fibers extending away from the inclusion. Chlamydial outer membrane components, in the absence of developmental forms, are found within these fibers. This colocalization may explain how chlamydial developmental form antigens are localized outside of the inclusion within infected cells.

Alternate JournalInfect. Immun.