Chlamydial development is blocked in host cells transfected with Chlamydophila caviae incA.

TitleChlamydial development is blocked in host cells transfected with Chlamydophila caviae incA.
Publication TypeJournal Article
Year of Publication2004
AuthorsAlzhanov D, Barnes J, Hruby DE, Rockey DD
JournalBMC microbiology
Volume4
Pagination24
Date Published2004 Jul 1
ISSN1471-2180
KeywordsAnimals, Bacterial Proteins, Cell Line, Cell Line, Tumor, Chlamydia trachomatis, Chlamydophila, CHO Cells, Cricetinae, Cricetulus, Cytoplasm, Genetic Vectors, Hela Cells, Humans, Membrane Proteins, Models, Genetic, Phosphoproteins, Transfection, Vaccinia virus
Abstract

Chlamydiae produce a set of proteins, termed Inc proteins, that are localized to the inclusion membrane and exposed to the host cell cytosol. Little information exists regarding the interaction of Inc proteins with the eukaryotic cell. To examine these interactions, Vaccinia virus vectors and mammalian plasmid-based systems were used to express inc genes in mammalian cells.
Alternate JournalBMC Microbiol.