Clinical, ultrasonographic, and laboratory findings in 12 llamas and 12 alpacas with malignant round cell tumors.

TitleClinical, ultrasonographic, and laboratory findings in 12 llamas and 12 alpacas with malignant round cell tumors.
Publication TypeJournal Article
Year of Publication2010
AuthorsMartin JM, Valentine BA, Cebra CK
JournalThe Canadian veterinary journal. La revue vétérinaire canadienne
Volume51
Issue12
Pagination1379-82
Date Published2010 Dec
ISSN0008-5286
KeywordsAnimals, Blood Cell Count, Blood Chemical Analysis, Camelids, New World, Female, Male, Neoplasms, Retrospective Studies, Weight Loss
Abstract

Clinical signs, duration of illness, clinicopathologic findings, and ultrasonographic findings were evaluated in 12 llamas and 12 alpacas with malignant round cell tumors (MRCT). All but 1 animal died or was euthanized. Common clinical findings were anorexia, recumbency or weakness, and weight loss or poor growth. Peripheral lymphadenomegaly occurred in only 7 animals and was detected more often at necropsy than during physical examination. Common clinicopathologic abnormalities were hypoalbuminemia, acidosis, azotemia, anemia, hyperglycemia, and neutrophilia. Ultrasonography detected tumors in 4/6 animals. Cytologic evaluation of fluid or tissue aspirates or histopathology of biopsy tissue was diagnostic in 5/6 cases. A clinical course of 2 wk or less prior to death or euthanasia was more common in animals ≤ 2 y of age (9/11) than in older animals (6/13). Regular examination of camelids to include clinical pathology and evaluation of peripheral lymph nodes may result in early detection of MCRT.

DOI10.1111/j.1365-3164.2011.00980.x
Alternate JournalCan. Vet. J.