Comparison of the levels of heat resistance of wild-type, cpe knockout, and cpe plasmid-cured Clostridium perfringens type A strains.

TitleComparison of the levels of heat resistance of wild-type, cpe knockout, and cpe plasmid-cured Clostridium perfringens type A strains.
Publication TypeJournal Article
Year of Publication2005
AuthorsRaju D, Sarker MR
JournalApplied and environmental microbiology
Volume71
Issue11
Pagination7618-20
Date Published2005 Nov
ISSN0099-2240
KeywordsBacterial Toxins, Calcium-Binding Proteins, Clostridium perfringens, Enterotoxins, Gene Deletion, Gene Expression Regulation, Bacterial, Heat-Shock Response, Hot Temperature, Plasmids, Spores, Bacterial, Type C Phospholipases
Abstract

An enterotoxin (cpe) plasmid was cured from a Clostridium perfringens non-food-borne gastrointestinal disease (NFBGID) isolate, and the heat resistance levels of wild-type, cpe knockout, and cpe plasmid-cured strains were compared. Our results demonstrated that (i) wild-type cpe has no influence in mediating high-level heat resistance in C. perfringens and (ii) the cpe plasmid does not confer heat sensitivity on NFBGID isolates.

Alternate JournalAppl. Environ. Microbiol.