- Future Students
- Current Students
- Faculty & Staff
Comparison of lidocaine, xylazine, and xylazine/lidocaine for caudal epidural analgesia in horses.
|Title||Comparison of lidocaine, xylazine, and xylazine/lidocaine for caudal epidural analgesia in horses.|
|Publication Type||Journal Article|
|Year of Publication||1992|
|Authors||Grubb TL, Riebold TW, Huber MJ|
|Journal||Journal of the American Veterinary Medical Association|
|Date Published||1992 Oct 15|
|Keywords||Analgesia, Epidural, Animals, Ataxia, Catheters, Indwelling, Drug Combinations, Female, Horses, Lidocaine, Male, Penis, Pulse, Respiration, Xylazine|
Caudal epidural analgesia was achieved in 6 adult horses on 3 successive occasions at weekly intervals by injection of lidocaine, xylazine, and a combination of lidocaine/xylazine through indwelling epidural catheters. Analgesia was defined as a lack of response to pinprick and hemostat pressure in the skin of the perineal area. A significant (P < 0.05) difference was not found for time of onset of analgesia between lidocaine (4.3 +/- 0.8 minutes, mean +/- SEM) and the lidocaine/xylazine combination (5.3 +/- 1.3 minutes). Time to onset of analgesia after administration of xylazine was significantly (P < 0.05) longer (32.0 +/- 3.4 minutes) than that for either of the other 2 treatments. Duration of analgesia was significantly (P < 0.05) longer for the combination (329.8 +/- 6.2 minutes) than for either drug used alone (lidocaine, 87.2 +/- 7.5 minutes; xylazine, 204.2 +/- 12.9 minutes). Pulse and respiratory rates were not significantly altered by any of the drugs. Neurologic sequelae were not clinically apparent after administration of the drugs or after chronic epidural catheterization.
|Alternate Journal||J. Am. Vet. Med. Assoc.|