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Effects of exenatide on plasma glucose and insulin concentrations in alpacas.
|Title||Effects of exenatide on plasma glucose and insulin concentrations in alpacas.|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Smith CC, Cebra CK|
|Journal||Journal of veterinary internal medicine / American College of Veterinary Internal Medicine|
|Date Published||2009 Jul-Aug|
|Keywords||Animals, Blood Glucose, Camelids, New World, Dose-Response Relationship, Drug, Female, Hypoglycemic Agents, Insulin, Male, Peptides, Venoms|
Exenatide is a degradation-resistant glucagon-like peptide 1 agonist used in the treatment of diabetes mellitus. It enhances the insulin response to hyperglycemia. Because of a poor insulin response, adult camelids are susceptible to hyperglycemia from stress, glucose administration, or energy metabolism disorders. Insulin often is administered to decrease plasma glucose concentration, but this approach has disadvantages such as the risk of hypoglycemia. Noninsulin medications targeting the incretin hormone pathway, such as exenatide, are providing alternate treatment options.
|Alternate Journal||J. Vet. Intern. Med.|