<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yu, Zhen</style></author><author><style face="normal" font="default" size="100%">Chung, Woon-Gye</style></author><author><style face="normal" font="default" size="100%">Sloat, Brian R</style></author><author><style face="normal" font="default" size="100%">Löhr, Christiane V</style></author><author><style face="normal" font="default" size="100%">Weiss, Richard</style></author><author><style face="normal" font="default" size="100%">Rodriguez, B Leticia</style></author><author><style face="normal" font="default" size="100%">Li, Xinran</style></author><author><style face="normal" font="default" size="100%">Cui, Zhengrong</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The extent of the uptake of plasmid into the skin determines the immune responses induced by a DNA vaccine applied topically onto the skin.</style></title><secondary-title><style face="normal" font="default" size="100%">The Journal of pharmacy and pharmacology</style></secondary-title><alt-title><style face="normal" font="default" size="100%">J. Pharm. Pharmacol.</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2011</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2011 Feb</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">63</style></volume><pages><style face="normal" font="default" size="100%">199-205</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Non-invasive immunization by application of plasmid DNA topically onto the skin is an attractive immunization approach. However, the immune responses induced are generally weak. Previously, we showed that the antibody responses induced by topical DNA vaccine are significantly enhanced when hair follicles in the application area are induced into the anagen (growth) stage by hair plucking. In the present study, we further investigated the mechanism of immune enhancement.</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/21235583?dopt=Abstract</style></custom1></record></records></xml>