<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Noonan, Curtis W</style></author><author><style face="normal" font="default" size="100%">Reif, John S</style></author><author><style face="normal" font="default" size="100%">Burch, James B</style></author><author><style face="normal" font="default" size="100%">Ichinose, Travers Y</style></author><author><style face="normal" font="default" size="100%">Yost, Michael G</style></author><author><style face="normal" font="default" size="100%">Magnusson, Kathy R</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Relationship between amyloid beta protein and melatonin metabolite in a study of electric utility workers.</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine</style></secondary-title><alt-title><style face="normal" font="default" size="100%">J. Occup. Environ. Med.</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Alzheimer Disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Amyloid beta-Peptides</style></keyword><keyword><style  face="normal" font="default" size="100%">Electromagnetic Fields</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Melatonin</style></keyword><keyword><style  face="normal" font="default" size="100%">Middle Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Occupational Exposure</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2002</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2002 Aug</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">44</style></volume><pages><style face="normal" font="default" size="100%">769-75</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">This study assessed the relationship between occupational magnetic field exposure, the urinary melatonin metabolite 6-hydroxymelatonin sulfate (6-OHMS), and concentrations of blood-borne soluble amyloid beta (A beta), a protein associated with the hallmark lesions of Alzheimer's disease (AD). Blood and urine samples were obtained from male electric utility workers (n = 60) to quantify two lengths of the protein in plasma, A beta (amino acids 1-40) and A beta (1-42), and the urinary concentrations of 6-OHMS. Average A beta levels were positively associated with categories of magnetic field exposure, but this relationship was weak and did not achieve statistical significance. The melatonin metabolite was inversely correlated with A beta (1-42) and the ratio of A beta (1-42) to A beta (1-40). This observation is consistent with recent in vitro data and provides a plausible mechanism for the association between magnetic field exposure and AD that has been observed in some studies.</style></abstract><issue><style face="normal" font="default" size="100%">8</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/12185798?dopt=Abstract</style></custom1></record></records></xml>