Gas chromatography-mass spectrometry assay for determination of Ntau-methylhistamine concentration in canine urine specimens and fecal extracts.

TitleGas chromatography-mass spectrometry assay for determination of Ntau-methylhistamine concentration in canine urine specimens and fecal extracts.
Publication TypeJournal Article
Year of Publication2009
AuthorsRuaux CG, Wright JM, Steiner JM, Williams DA
JournalAmerican journal of veterinary research
Volume70
Issue2
Pagination167-71
Date Published2009 Feb
ISSN0002-9645
KeywordsAnimals, Dog Diseases, Dogs, Feces, Gas Chromatography-Mass Spectrometry, Mastocytosis, Methylhistamines, Protein-Losing Enteropathies, Validation Studies as Topic
Abstract

To develop and validate a gas chromatography-mass spectrometry (GC-MS) method for determination of Ntau-methylhistamine (NMH) concentration in canine urine and fecal extracts and to assess urinary NMH concentrations in dogs with mast cell neoplasia and fecal NMH concentrations in dogs with protein-losing enteropathy.

Alternate JournalAm. J. Vet. Res.