Hepatic volume estimation using quantitative computed tomography in dogs with portosystemic shunts.

TitleHepatic volume estimation using quantitative computed tomography in dogs with portosystemic shunts.
Publication TypeJournal Article
Year of Publication2007
AuthorsStieger SM, Zwingenberger A, Pollard RE, Kyles AE, Wisner ER
JournalVeterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Volume48
Issue5
Pagination409-13
Date Published2007 Sep-Oct
ISSN1058-8183
KeywordsAnimals, Contrast Media, Dog Diseases, Dogs, Female, Hypertension, Portal, Liver, Male, Postoperative Complications, Tomography, X-Ray Computed
Abstract

The purpose of this study was to use quantitative computed tomography (CT) to estimate liver volume in dogs with a portosystemic shunt and to compare the liver volume in normal dogs to dogs with a shunt. Twenty-one dogs with a portosystemic shunt underwent contrast-enhanced abdominal CT for shunt characterization and preoperative planning. Six dogs without clinical signs relating to liver disease were used as a control group. In addition, liver volume was compared before and 2-4 months after surgical shunt attenuation in three dogs. All studies followed established clinical imaging protocols. Liver margins were defined on each image using an operator-defined region of interest and hepatic volume renderings were produced from which the liver volume was quantitatively estimated. There was a statistically significant association between liver volume and body weight in control and shunt dogs (r = 0.909 and 0.899, respectively, P < 0.01). Liver volume normalized to body weight was 15.5 +/- 5.2 cm3/kg in affected dogs and 24.5 +/- 5.6 cm3/kg in control dogs. Based on postligation CT studies in three affected dogs, liver volume increased by 43%, 51%, and 62%. Hepatic volume estimation may be a clinically useful parameter in the initial and postsurgical evaluation of dogs with portosystemic shunts.

Alternate JournalVet Radiol Ultrasound