Impact of intense, longitudinal retreatment with praziquantel on cure rates of schistosomiasis mansoni in a cohort of occupationally exposed adults in western Kenya.

TitleImpact of intense, longitudinal retreatment with praziquantel on cure rates of schistosomiasis mansoni in a cohort of occupationally exposed adults in western Kenya.
Publication TypeJournal Article
Year of Publication2009
AuthorsBlack CL, Steinauer ML, Mwinzi PNM, Evan Secor W, Karanja DMS, Colley DG
JournalTropical medicine & international health : TM & IH
Volume14
Issue4
Pagination450-7
Date Published2009 Apr
ISSN1365-3156
KeywordsAdult, Animals, Anthelmintics, Drug Resistance, HIV Infections, Humans, Liver Diseases, Parasitic, Logistic Models, Longitudinal Studies, Male, Multivariate Analysis, Parasite Egg Count, Praziquantel, Schistosomiasis mansoni
Abstract

To investigate trends in the efficacy of praziquantel (PZQ) suggestive of the emergence of drug resistance against Schistosoma mansoni infection after 12.5 years of intense, repeated use in a small geographic area along the shores of Lake Victoria.

Alternate JournalTrop. Med. Int. Health