Inheritance of recurrent exertional rhabdomyolysis in thoroughbreds.

TitleInheritance of recurrent exertional rhabdomyolysis in thoroughbreds.
Publication TypeJournal Article
Year of Publication2005
AuthorsDranchak PK, Valberg SJ, Onan GW, Gallant EM, MacLeay JM, McKenzie EC, De La Corte FD, Ekenstedt K, Mickelson JR
JournalJournal of the American Veterinary Medical Association
Date Published2005 Sep 1
KeywordsAnesthetics, Inhalation, Animals, Biopsy, Caffeine, Case-Control Studies, Central Nervous System Stimulants, Female, Genes, Dominant, Halothane, Horse Diseases, Horses, Male, Muscle Contraction, Muscle, Skeletal, Pedigree, Physical Conditioning, Animal, Recurrence, Rhabdomyolysis

To develop a diagnostic test for recurrent exertional rhabdomyolysis (RER) in Thoroughbreds that relied on in vitro contracture of muscle biopsy specimens and determine whether the inheritance pattern of RER diagnosed on the basis of this contracture test was consistent with an autosomal dominant trait.

Alternate JournalJ. Am. Vet. Med. Assoc.