Myonecrosis in three horses with colic: evidence for endotoxic injury.

TitleMyonecrosis in three horses with colic: evidence for endotoxic injury.
Publication TypeJournal Article
Year of Publication2007
AuthorsValentine BA, Löhr CV
JournalThe Veterinary record
Volume161
Issue23
Pagination786-9
Date Published2007 Dec 8
ISSN0042-4900
KeywordsAnimals, Aspartate Aminotransferases, Colic, Creatine Kinase, Fatal Outcome, Female, Horse Diseases, Horses, Male, Muscle, Skeletal, Muscular Diseases, Necrosis, Shock, Septic
Abstract

Three horses with colic, clinical evidence of endotoxaemia and high serum activities of creatine kinase and aspartate aminotransferase were examined postmortem. The horses were diagnosed with severe ulcerative colitis, pyloric ulceration and stenosis with colonic sand impaction, and colonic obstruction due to faecaliths. There was no gross or histological evidence of muscle trauma. Their semimembranosus muscles had scattered acute to subacute segmental necrosis of the myofibres, suggestive of endotoxin-induced muscle injury.

Alternate JournalVet. Rec.