Recombinant cytokines for controlling mycobacterial infections.

TitleRecombinant cytokines for controlling mycobacterial infections.
Publication TypeJournal Article
Year of Publication1995
AuthorsBermudez LE, Kaplan G
JournalTrends in microbiology
Date Published1995 Jan
KeywordsCytokines, Humans, Leprosy, Mycobacterium avium-intracellulare Infection, Mycobacterium Infections, Recombinant Proteins, Tuberculosis

Knowing how mycobacteria exploit host cytokines to survive and which cytokines have important roles in host defense against mycobacteria should allow the use of these molecules in the treatment of mycobacterial infections. Both interleukin 2 and interferon gamma have been used to treat patients with leprosy, and granulocyte-macrophage colony-stimulating factor is presently being administered to AIDS patients infected with Mycobacterium avium.

Alternate JournalTrends Microbiol.