Secondary renal tubular acidosis in a Hereford calf.

TitleSecondary renal tubular acidosis in a Hereford calf.
Publication TypeJournal Article
Year of Publication2011
AuthorsHardefeldt LY, Poulsen KP, Darien BJ
JournalVeterinary clinical pathology / American Society for Veterinary Clinical Pathology
Date Published2011 Jun
KeywordsAcidosis, Renal Tubular, Animals, Bicarbonates, Blood Gas Analysis, Buffers, Cattle, Cattle Diseases, Female, Salmonella enterica, Salmonella Infections, Animal

A 3-month-old Hereford heifer calf was presented for lethargy. Blood gas analysis and plasma biochemical testing revealed severe metabolic acidosis, azotemia, hyponatremia, hyperchloremia, and normal anion gap. Results of a urinalysis were consistent with acute tubular necrosis with inadequate acidification of urine based on the degree of acidemia. Salmonella enterica serovar agona was cultured from both urine and feces. The calf was treated with intravenous polyionic fluids, bicarbonate, and antimicrobials. Acidosis and azotemia resolved, and 4 months following initial presentation the heifer was clinically normal.

Alternate JournalVet Clin Pathol