TolC affects virulence gene expression in Vibrio cholerae.

TitleTolC affects virulence gene expression in Vibrio cholerae.
Publication TypeJournal Article
Year of Publication2011
AuthorsMinato Y, Siefken RL, Häse CC
JournalJournal of bacteriology
Volume193
Issue20
Pagination5850-2
Date Published2011 Oct
ISSN1098-5530
KeywordsBacterial Proteins, Gene Expression Regulation, Bacterial, Membrane Transport Proteins, Mutation, Transcription Factors, Up-Regulation, Vibrio cholerae, Virulence Factors
Abstract

A Vibrio cholerae tolC mutant showed increased toxT expression in M9 medium, but not in the presence of four amino acids that induce cholera toxin production, and in LB with high osmolarity but not high pH or temperature. TolC did not affect expression of other regulatory genes in the ToxR regulon.

DOI10.1128/JB.05222-11
Alternate JournalJ. Bacteriol.