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Use of corticosteroids and aurothioglucose in a pygmy goat with pemphigus foliaceus.
|Title||Use of corticosteroids and aurothioglucose in a pygmy goat with pemphigus foliaceus.|
|Publication Type||Journal Article|
|Year of Publication||1995|
|Authors||Valdez RA, Gelberg HB, Morin DE, Zuckermann FA|
|Journal||Journal of the American Veterinary Medical Association|
|Date Published||1995 Sep 15|
|Keywords||Alopecia, Animals, Aurothioglucose, Dermatitis, Seborrheic, Diagnosis, Differential, Drug Therapy, Combination, Female, Follow-Up Studies, Goat Diseases, Goats, Pemphigus, Prednisolone|
Pemphigus foliaceus was diagnosed in a 20-month-old female pygmy goat. The goat had a 3-month history of chronic exfoliative dermatitis and was examined after developing alopecia and severe, asymmetric, diffuse flakes of dry, nonadherent skin scales. Pemphigus foliaceus was diagnosed on the basis of dermatohistologic findings and was confirmed by analysis of results of direct immunofluorescence testing of perilesional specimens obtained by use of a punch biopsy. The goat was successfully treated with prednisolone (immunosuppressive induction dosage; 1 mg/kg of body weight, IM, q 12 h). Remission was achieved in 1 week and was maintained by use of prednisolone (immunosuppressive maintenance dosage; 1 mg/kg, IM, q 48 h). Treatment with aurothioglucose (1 mg/kg, IM, q 7 d) that was initiated during administration of prednisolone and was continued after discontinuation of corticosteroid administration failed to prevent redevelopment of pemphigus foliaceus.
|Alternate Journal||J. Am. Vet. Med. Assoc.|