The use of monoclonal antibodies in the diagnosis of partially treated Pseudomonas aeruginosa meningitis: patient report.

TitleThe use of monoclonal antibodies in the diagnosis of partially treated Pseudomonas aeruginosa meningitis: patient report.
Publication TypeJournal Article
Year of Publication1986
AuthorsBermudez LE
JournalBrazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.]
Volume19
Issue2
Pagination159-65
Date Published1986
ISSN0100-879X
KeywordsAnti-Bacterial Agents, Antibodies, Monoclonal, Antigens, Bacterial, Cross Reactions, Female, Humans, Meningitis, Middle Aged, Pseudomonas aeruginosa, Pseudomonas Infections
Abstract

The objective of this study was to evaluate the efficacy of mouse anti-pseudomonas monoclonal antibodies to detect small numbers of pathogenic pseudomonas in the spinal fluid of a patient who had been treated with antibiotics for meningitis. Anti-605 monoclonal antibody against Pseudomonas aeruginosa PAC 605, a rough mutant, showed sensitivity similar to that of anti-Fisher 1 monoclonal antibody in detecting P. aeruginosa Fisher 1 antigens in boiled spinal fluid drawn from a patient with a P. aeruginosa perispinal abscess and partially treated meningitis.

Alternate JournalBraz. J. Med. Biol. Res.