TitleInfluence of ivermectin and clorsulon treatment on productivity of a cow-calf herd on the southern Oregon coast.
Publication TypeJournal Article
Year of Publication1992
AuthorsRickard, LG, Zimmerman, GL, Hoberg, EP, Bishop-Stewart, JK, Pettitt, RJ
JournalVet Parasitol
Date Published1992 Feb
KeywordsAdministration, Oral, Animals, Antiplatyhelmintic Agents, Cattle, Cattle Diseases, Fasciola hepatica, Fascioliasis, Female, Helminthiasis, Helminthiasis, Animal, Injections, Subcutaneous, Ivermectin, Male, Nematode Infections, Oregon, Parasite Egg Count, Pregnancy, Pregnancy Complications, Infectious, Reproduction, Sulfanilamides

The reproductive performance of beef cows and the weight gain of their calves was evaluated after oral administration of clorsulon or clorsulon in combination with the subcutaneous administration of ivermectin. One hundred and fifty pregnant cows harboring infections of Fasciola hepatica were assigned to one of three treatment groups: Group 1 comprising 50 unmedicated controls; Group 2, 50 cows treated with clorsulon orally at 7 mg kg-1; Group 3, 50 cows treated with clorsulon orally at 7 mg kg-1 and ivermectin subcutaneously at 200 micrograms kg-1. Weights and body condition scores of the cows were measured and fecal and blood samples were taken at trial initiation and days 158 and 270. Pregnancy status was also determined at day 270. Weights and body condition scores were measured for the calves at days 158 and 270. Adjusted 205 day weaning weight of the calves was calculated and analyzed for differences between treatment groups. Four sets of tracer calves were used periodically throughout the trial to monitor the helminth challenge to the herd. Both gastro-intestinal nematodes and liver flukes were transmitted to the tracer calves during the entire trial. Even in the face of continual helminth challenge, beef cows treated with combined clorsulon/ivermectin conceived approximately 2 weeks earlier than their untreated counterparts and their calves had better body condition scores and weights than untreated calves.

Alternate JournalVet. Parasitol.
PubMed ID1561761