Carlson College of Veterinary Medicine

P. E. Chappell, Schneider, J. S., Kim, P., Xu, M., Lydon, J. P., O'Malley, B. W., and Levine, J. E., “Absence of gonadotropin surges and gonadotropin-releasing hormone self-priming in ovariectomized (OVX), estrogen (E2)-treated, progesterone receptor knockout (PRKO) mice.”, Endocrinology, vol. 140, no. 8, pp. 3653-8, 1999.

S. Zhen, Dunn, I. C., Wray, S., Liu, Y., Chappell, P. E., Levine, J. E., and Radovick, S., “An alternative gonadotropin-releasing hormone (GnRH) RNA splicing product found in cultured GnRH neurons and mouse hypothalamus.”, The Journal of biological chemistry, vol. 272, no. 19, pp. 12620-5, 1997.

H. M. Broughton, Govender, D., Shikwambana, P., Chappell, P. E., and Jolles, A. E., “BRIDGING GAPS BETWEEN ZOO AND WILDLIFE MEDICINE: ESTABLISHING REFERENCE INTERVALS FOR FREE-RANGING AFRICAN LIONS (PANTHERA LEO).”, J Zoo Wildl Med, vol. 48, no. 2, pp. 298-311, 2017.

K. P. Tolson and Chappell, P. E., “The Changes They are A-Timed: Metabolism, Endogenous Clocks, and the Timing of Puberty.”, Frontiers in endocrinology, vol. 3, p. 45, 2012.

P. Bebas, Goodall, C. P., Majewska, M., Neumann, A., Giebultowicz, J. M., and Chappell, P. E., “Circadian clock and output genes are rhythmically expressed in extratesticular ducts and accessory organs of mice.”, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol. 23, no. 2, pp. 523-33, 2009.

J. D. Alvarez, Hansen, A., Ord, T., Bebas, P., Chappell, P. E., Giebultowicz, J. M., Williams, C., Moss, S., and Sehgal, A., “The circadian clock protein BMAL1 is necessary for fertility and proper testosterone production in mice.”, Journal of biological rhythms, vol. 23, no. 1, pp. 26-36, 2008.

P. E. Chappell, White, R. S., and Mellon, P. L., “Circadian gene expression regulates pulsatile gonadotropin-releasing hormone (GnRH) secretory patterns in the hypothalamic GnRH-secreting GT1-7 cell line.”, The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 23, no. 35, pp. 11202-13, 2003.

P. E. Chappell, “Clocks and the black box: circadian influences on gonadotropin-releasing hormone secretion.”, Journal of neuroendocrinology, vol. 17, no. 2, pp. 119-30, 2005.

K. J. Tonsfeldt and Chappell, P. E., “Clocks on top: the role of the circadian clock in the hypothalamic and pituitary regulation of endocrine physiology.”, Molecular and cellular endocrinology, vol. 349, no. 1, pp. 3-12, 2012.

P. E. Chappell, Lydon, J. P., Conneely, O. M., O'Malley, B. W., and Levine, J. E., “Endocrine defects in mice carrying a null mutation for the progesterone receptor gene.”, Endocrinology, vol. 138, no. 10, pp. 4147-52, 1997.

C. L. Sisk, Richardson, H. N., Chappell, P. E., and Levine, J. E., “In vivo gonadotropin-releasing hormone secretion in female rats during peripubertal development and on proestrus.”, Endocrinology, vol. 142, no. 7, pp. 2929-36, 2001.

D. Meritet, Townsend, K. L., M Gorman, E., Chappell, P. E., Kelly, L., and Russell, D. S., “Investigating the Effects of Error Management Training versus Error Avoidance Training on the Performance of Veterinary Students Learning to Tie Surgical Knots.”, J Vet Med Educ, p. e20190012, 2020.

P. E. Chappell, Goodall, C. P., Tonsfeldt, K. J., White, R. S., Bredeweg, E., and Latham, K. L., “Modulation of gonadotrophin-releasing hormone secretion by an endogenous circadian clock.”, Journal of neuroendocrinology, vol. 21, no. 4, pp. 339-45, 2009.

K. J. Tonsfeldt, Goodall, C. P., Latham, K. L., and Chappell, P. E., “Oestrogen induces rhythmic expression of the Kisspeptin-1 receptor GPR54 in hypothalamic gonadotrophin-releasing hormone-secreting GT1-7 cells.”, Journal of neuroendocrinology, vol. 23, no. 9, pp. 823-30, 2011.

R. Sasson, Dearth, R. K., White, R. S., Chappell, P. E., and Mellon, P. L., “Orexin A induces GnRH gene expression and secretion from GT1-7 hypothalamic GnRH neurons.”, Neuroendocrinology, vol. 84, no. 6, pp. 353-63, 2006.

J. E. Levine, Chappell, P. E., Schneider, J. S., Sleiter, N. C., and Szabo, M., “Progesterone receptors as neuroendocrine integrators.”, Frontiers in neuroendocrinology, vol. 22, no. 2, pp. 69-106, 2001.

P. E. Chappell, Lee, J., and Levine, J. E., “Stimulation of gonadotropin-releasing hormone surges by estrogen. II. Role of cyclic adenosine 3'5'-monophosphate.”, Endocrinology, vol. 141, no. 4, pp. 1486-92, 2000.

P. E. Chappell and Levine, J. E., “Stimulation of gonadotropin-releasing hormone surges by estrogen. I. Role of hypothalamic progesterone receptors.”, Endocrinology, vol. 141, no. 4, pp. 1477-85, 2000.