Carlson College of Veterinary Medicine

G. Green, Johnson, S. M., Costello, H., Brakel, K., Harder, O., Oomens, A. G., Peeples, M. E., Moulton, H. M., and Niewiesk, S., “CX3CR1 Is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats.”, J Virol, vol. 95, no. 16, p. e0001021, 2021.

Y. Dang, van Heusden, C., Nickerson, V., Chung, F., Wang, Y., Quinney, N. L., Gentzsch, M., Randell, S. H., Moulton, H. M., Kole, R., Ni, A., Juliano, R. L., and Kreda, S. M., “Enhanced delivery of peptide-morpholino oligonucleotides with a small molecule to correct splicing defects in the lung.”, Nucleic Acids Res, vol. 49, no. 11, pp. 6100-6113, 2021.

D. Bestle, Limburg, H., Kruhl, D., Harbig, A., Stein, D. A., Moulton, H. M., Matrosovich, M., Abdelwhab, E. M., Stech, J., and Böttcher-Friebertshäuser, E., “Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells.”, J Virol, vol. 95, no. 20, p. e0090621, 2021.

L. Martin-Sancho, Tripathi, S., Rodriguez-Frandsen, A., Pache, L., Sanchez-Aparicio, M., McGregor, M. J., Haas, K. M., Swaney, D. L., Nguyen, T. T., Mamede, J. I., Churas, C., Pratt, D., Rosenthal, S. B., Riva, L., Nguyen, C., Beltran-Raygoza, N., Soonthornvacharin, S., Wang, G., Jimenez-Morales, D., De Jesus, P. D., Moulton, H. M., Stein, D. A., Chang, M. W., Benner, C., Ideker, T., Albrecht, R. A., Hultquist, J. F., Krogan, N. J., García-Sastre, A., and Chanda, S. K., “Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy.”, Nat Microbiol, vol. 6, no. 10, pp. 1319-1333, 2021.

D. Bestle, Heindl, M. Ruth, Limburg, H., van, T. Van Lam, Pilgram, O., Moulton, H. M., Stein, D. A., Hardes, K., Eickmann, M., Dolnik, O., Rohde, C., Klenk, H. - D., Garten, W., Steinmetzer, T., and Böttcher-Friebertshäuser, E., “TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells.”, Life Sci Alliance, vol. 3, no. 9, 2020.

L. Louis Seifert, Si, C., Saha, D., Sadic, M., de Vries, M., Ballentine, S., Briley, A., Wang, G., Valero-Jimenez, A. M., Mohamed, A., Schaefer, U., Moulton, H. M., García-Sastre, A., Tripathi, S., Rosenberg, B. R., and Dittmann, M., “The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response.”, PLoS Pathog, vol. 15, no. 11, p. e1007634, 2019.

H. Limburg, Harbig, A., Bestle, D., Stein, D. A., Moulton, H. M., Jaeger, J., Janga, H., Hardes, K., Koepke, J., Schulte, L., Koczulla, A. Rembert, Schmeck, B., Klenk, H. - D., and Böttcher-Friebertshäuser, E., “TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes.”, J Virol, vol. 93, no. 21, 2019.

S. Soonthornvacharin, Rodriguez-Frandsen, A., Zhou, Y., Galvez, F., Huffmaster, N. J., Tripathi, S., Balasubramaniam, V. R. M. T., Inoue, A., de Castro, E., Moulton, H. M., Stein, D. A., Sánchez-Aparicio, M. Teresa, De Jesus, P. D., Nguyen, Q., König, R., Krogan, N. J., García-Sastre, A., Yoh, S. M., and Chanda, S. K., “Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.”, Nat Microbiol, vol. 2, p. 17022, 2017.

S. Tripathi, Pohl, M. O., Zhou, Y., Rodriguez-Frandsen, A., Wang, G., Stein, D. A., Moulton, H. M., DeJesus, P., Che, J., Mulder, L. C. F., Yángüez, E., Andenmatten, D., Pache, L., Manicassamy, B., Albrecht, R. A., Gonzalez, M. G., Nguyen, Q., Brass, A., Elledge, S., White, M., Shapira, S., Hacohen, N., Karlas, A., Meyer, T. F., Shales, M., Gatorano, A., Johnson, J. R., Jang, G., Johnson, T., Verschueren, E., Sanders, D., Krogan, N., Shaw, M., König, R., Stertz, S., García-Sastre, A., and Chanda, S. K., “Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.”, Cell Host Microbe, vol. 18, no. 6, pp. 723-35, 2015.

R. Rajsbaum, Versteeg, G. A., Schmid, S., Maestre, A. M., Belicha-Villanueva, A., Martínez-Romero, C., Patel, J. R., Morrison, J., Pisanelli, G., Miorin, L., Laurent-Rolle, M., Moulton, H. M., Stein, D. A., Fernandez-Sesma, A., tenOever, B. R., and García-Sastre, A., “Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.”, Immunity, vol. 40, no. 6, pp. 880-95, 2014.

H. M. Moulton, “In vivo delivery of morpholino oligos by cell-penetrating peptides.”, Curr Pharm Des, vol. 19, no. 16, pp. 2963-9, 2013.

Q. Wang, Yin, H., Camelliti, P., Betts, C., Moulton, H. M., Lee, H., Saleh, A. F., Gait, M. J., and Wood, M. J. A., “In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy.”, J Gene Med, vol. 12, no. 4, pp. 354-64, 2010.

H. M. Moulton and Moulton, J. D., “Morpholinos and their peptide conjugates: therapeutic promise and challenge for Duchenne muscular dystrophy.”, Biochim Biophys Acta, vol. 1798, no. 12, pp. 2296-303, 2010.