Found 16 results
Author Title [ Type(Desc)] Year
Filters: Keyword is Morpholinos  [Clear All Filters]
Journal Article
G. Chow, Morcos, P. A., and Moulton, H. M., “Aggregation and Disaggregation of Morpholino Oligomers in Solution.”, Methods Mol Biol, vol. 1565, pp. 31-38, 2017.
X. Gao, Ran, N., Dong, X., Zuo, B., Yang, R., Zhou, Q., Moulton, H. M., Seow, Y., and Yin, H., “Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy.”, Sci Transl Med, vol. 10, no. 444, 2018.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M., and Buchmeier, M. J., “Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors.”, Antimicrob Agents Chemother, vol. 55, no. 10, pp. 4631-8, 2011.
A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H. M., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., “Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.”, Hum Mol Genet, vol. 20, no. 3, pp. 413-21, 2011.
M. Nizzardo, Simone, C., Salani, S., Ruepp, M. - D., Rizzo, F., Ruggieri, M., Zanetta, C., Brajkovic, S., Moulton, H. M., Müehlemann, O., Bresolin, N., Comi, G. P., and Corti, S., “Effect of combined systemic and local morpholino treatment on the spinal muscular atrophy Δ7 mouse model phenotype.”, Clin Ther, vol. 36, no. 3, pp. 340-56.e5, 2014.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H. M., and Yin, H., “Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice.”, Mol Ther, vol. 22, no. 7, pp. 1333-1341, 2014.
Y. Echigoya, Nakamura, A., Nagata, T., Urasawa, N., Lim, K. Rowel Q., Trieu, N., Panesar, D., Kuraoka, M., Moulton, H. M., Saito, T., Aoki, Y., Iversen, P., Sazani, P., Kole, R., Maruyama, R., Partridge, T., Takeda, S. 'ichi, and Yokota, T., “Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy.”, Proc Natl Acad Sci U S A, vol. 114, no. 16, pp. 4213-4218, 2017.
Y. Dang, van Heusden, C., Nickerson, V., Chung, F., Wang, Y., Quinney, N. L., Gentzsch, M., Randell, S. H., Moulton, H. M., Kole, R., Ni, A., Juliano, R. L., and Kreda, S. M., “Enhanced delivery of peptide-morpholino oligonucleotides with a small molecule to correct splicing defects in the lung.”, Nucleic Acids Res, vol. 49, no. 11, pp. 6100-6113, 2021.
B. Wu, Cloer, C., Lu, P., Milazi, S., Shaban, M., Shah, S. N., Marston-Poe, L., Moulton, H. M., and Lu, Q. L., “Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice.”, Gene Ther, vol. 21, no. 9, pp. 785-93, 2014.
H. Yin, Moulton, H. M., Betts, C., Merritt, T., Seow, Y., Ashraf, S., Wang, Q., Boutilier, J., and Wood, M. Ja, “Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO.”, Mol Ther, vol. 18, no. 10, pp. 1822-9, 2010.
H. M. Moulton, “In vivo delivery of morpholino oligos by cell-penetrating peptides.”, Curr Pharm Des, vol. 19, no. 16, pp. 2963-9, 2013.
K. Rosenke, Leventhal, S., Moulton, H. M., Hatlevig, S., Hawman, D., Feldmann, H., and Stein, D. A., “Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers.”, J Antimicrob Chemother, vol. 76, no. 2, pp. 413-417, 2021.
N. Jearawiriyapaisarn, Moulton, H. M., Sazani, P., Kole, R., and Willis, M. S., “Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers.”, Cardiovasc Res, vol. 85, no. 3, pp. 444-53, 2010.
B. Wu, Lu, P., Cloer, C., Shaban, M., Grewal, S., Milazi, S., Shah, S. N., Moulton, H. M., and Lu, Q. Long, “Long-term rescue of dystrophin expression and improvement in muscle pathology and function in dystrophic mdx mice by peptide-conjugated morpholino.”, Am J Pathol, vol. 181, no. 2, pp. 392-400, 2012.
J. Kim, Clark, K., Barton, C., Tanguay, R., and Moulton, H. M., “A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers.”, Methods Mol Biol, vol. 1828, pp. 293-306, 2018.
J. Boutilier and Moulton, H. M., “Surface Plasmon Resonance-Based Concentration Determination Assay: Label-Free and Antibody-Free Quantification of Morpholinos.”, Methods Mol Biol, vol. 1565, pp. 251-263, 2017.