Found 86 results
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Journal Article
R. Abes, Moulton, H., Clair, P., Yang, S. - T., Abes, S., Melikov, K., Prevot, P., Youngblood, D. S., Iversen, P. L., Chernomordik, L. V., and Lebleu, B., Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies., Nucleic acids research, vol. 36, no. 20, pp. 6343-54, 2008.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H., and Buchmeier, M. J., Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors., Antimicrob Agents Chemother, vol. 55, no. 10, pp. 4631-8, 2011.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H., and Buchmeier, M. J., Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors., Antimicrobial agents and chemotherapy, vol. 55, no. 10, pp. 4631-8, 2011.
A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., Diaphragm rescue alone prevents heart dysfunction in dystrophic mice., Human molecular genetics, vol. 20, no. 3, pp. 413-21, 2011.
A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., Diaphragm rescue alone prevents heart dysfunction in dystrophic mice., Hum Mol Genet, vol. 20, no. 3, pp. 413-21, 2011.
S. Fletcher, Adams, A. M., Johnsen, R. D., Greer, K., Moulton, H., and Wilton, S. D., Dystrophin isoform induction in vivo by antisense-mediated alternative splicing., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 18, no. 6, pp. 1218-23, 2010.
S. Fletcher, Adams, A. M., Johnsen, R. D., Greer, K., Moulton, H., and Wilton, S. D., Dystrophin isoform induction in vivo by antisense-mediated alternative splicing., Mol Ther, vol. 18, no. 6, pp. 1218-23, 2010.
M. Nizzardo, Simone, C., Salani, S., Ruepp, M. - D., Rizzo, F., Ruggieri, M., Zanetta, C., Brajkovic, S., Moulton, H., Müehlemann, O., Bresolin, N., Comi, G. P., and Corti, S., Effect of combined systemic and local morpholino treatment on the spinal muscular atrophy Δ7 mouse model phenotype., Clin Ther, vol. 36, no. 3, pp. 340-56.e5, 2014.
M. Nizzardo, Simone, C., Salani, S., Ruepp, M. - D., Rizzo, F., Ruggieri, M., Zanetta, C., Brajkovic, S., Moulton, H., Müehlemann, O., Bresolin, N., Comi, G. P., and Corti, S., Effect of combined systemic and local morpholino treatment on the spinal muscular atrophy Δ7 mouse model phenotype., Clinical therapeutics, vol. 36, no. 3, pp. 340-56.e5, 2014.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H., and Yin, H., Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide-Morpholino Conjugate in Dystrophin-Deficient mdx Mice., Mol Ther, vol. 28, no. 10, pp. 2299-2301, 2020.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H., and Yin, H., Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice., Mol Ther, vol. 22, no. 7, pp. 1333-1341, 2014.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H., and Yin, H., Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 22, no. 7, pp. 1333-41, 2014.
B. Wu, Moulton, H., Iversen, P. L., Jiang, J., Li, J., Li, J., Spurney, C. F., Sali, A., Guerron, A. D., Nagaraju, K., Doran, T., Lu, P., Xiao, X., and Lu, Q. Long, Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer., Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 39, pp. 14814-9, 2008.
Y. Echigoya, Nakamura, A., Nagata, T., Urasawa, N., Lim, K. Rowel Q., Trieu, N., Panesar, D., Kuraoka, M., Moulton, H., Saito, T., Aoki, Y., Iversen, P., Sazani, P., Kole, R., Maruyama, R., Partridge, T., Takeda, S. 'ichi, and Yokota, T., Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy., Proc Natl Acad Sci U S A, vol. 114, no. 16, pp. 4213-4218, 2017.
L. Cao, Han, G., Lin, C., Gu, B., Gao, X., Moulton, H., Seow, Y., and Yin, H., Erratum: Fructose Promotes Uptake and Activity of Oligonucleotides with Different Chemistries in a Context-Dependent Manner in Mice., Mol Ther Nucleic Acids, vol. 22, pp. 1040-1042, 2020.
L. Louis Seifert, Si, C., Saha, D., Sadic, M., de Vries, M., Ballentine, S., Briley, A., Wang, G., Valero-Jimenez, A. M., Mohamed, A., Schaefer, U., Moulton, H., García-Sastre, A., Tripathi, S., Rosenberg, B. R., and Dittmann, M., The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response., PLoS Pathog, vol. 15, no. 11, p. e1007634, 2019.
B. Wu, Cloer, C., Lu, P., Milazi, S., Shaban, M., Shah, S. N., Marston-Poe, L., Moulton, H., and Lu, Q. L., Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice., Gene therapy, vol. 21, no. 9, pp. 785-93, 2014.
B. Wu, Cloer, C., Lu, P., Milazi, S., Shaban, M., Shah, S. N., Marston-Poe, L., Moulton, H., and Lu, Q. L., Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice., Gene Ther, vol. 21, no. 9, pp. 785-93, 2014.
H. Yin, Moulton, H., Betts, C., Merritt, T., Seow, Y., Ashraf, S., Wang, Q., Boutilier, J., and Wood, M. J. A., Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 18, no. 10, pp. 1822-9, 2010.
H. Yin, Moulton, H., Betts, C., Merritt, T., Seow, Y., Ashraf, S., Wang, Q., Boutilier, J., and Wood, M. Ja, Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO., Mol Ther, vol. 18, no. 10, pp. 1822-9, 2010.
H. Yin, Moulton, H., Betts, C., Seow, Y., Boutilier, J., Iverson, P. L., and Wood, M. J. A., A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice., Human molecular genetics, vol. 18, no. 22, pp. 4405-14, 2009.
G. Han, Gu, B., Lin, C., Ning, H., Song, J., Gao, X., Moulton, H., and Yin, H., Hexose Potentiates Peptide-Conjugated Morpholino Oligomer Efficacy in Cardiac Muscles of Dystrophic Mice in an Age-Dependent Manner., Mol Ther Nucleic Acids, vol. 18, pp. 341-350, 2019.
H. Moulton, Hase, M. C., Smith, K. M., and Iversen, P. L., HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers., Antisense & nucleic acid drug development, vol. 13, no. 1, pp. 31-43, 2003.
Q. Wang, Yin, H., Camelliti, P., Betts, C., Moulton, H., Lee, H., Saleh, A. F., Gait, M. J., and Wood, M. J. A., In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy., The journal of gene medicine, vol. 12, no. 4, pp. 354-64, 2010.
Q. Wang, Yin, H., Camelliti, P., Betts, C., Moulton, H., Lee, H., Saleh, A. F., Gait, M. J., and Wood, M. J. A., In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy., J Gene Med, vol. 12, no. 4, pp. 354-64, 2010.

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