Carlson College of Veterinary Medicine

H. Yin, Moulton, H. M., Betts, C., Merritt, T., Seow, Y., Ashraf, S., Wang, Q., Boutilier, J., and Wood, M. J. A., “Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO.”, Molecular therapy : the journal of the American Society of Gene Therapy, vol. 18, no. 10, pp. 1822-9, 2010.

H. Yin, Moulton, H. M., Betts, C., Merritt, T., Seow, Y., Ashraf, S., Wang, Q., Boutilier, J., and Wood, M. Ja, “Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO.”, Mol Ther, vol. 18, no. 10, pp. 1822-9, 2010.

H. Yin, Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Iverson, P. L., and Wood, M. J. A., “A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.”, Hum Mol Genet, vol. 28, no. 4, p. 699, 2019.

H. Yin, Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Iverson, P. L., and Wood, M. J. A., “A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.”, Human molecular genetics, vol. 18, no. 22, pp. 4405-14, 2009.

D. Bestle, Limburg, H., Kruhl, D., Harbig, A., Stein, D. A., Moulton, H. M., Matrosovich, M., Abdelwhab, E. M., Stech, J., and Böttcher-Friebertshäuser, E., “Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells.”, J Virol, vol. 95, no. 20, p. e0090621, 2021.

G. Han, Gu, B., Lin, C., Ning, H., Song, J., Gao, X., Moulton, H. M., and Yin, H., “Hexose Potentiates Peptide-Conjugated Morpholino Oligomer Efficacy in Cardiac Muscles of Dystrophic Mice in an Age-Dependent Manner.”, Mol Ther Nucleic Acids, vol. 18, pp. 341-350, 2019.

H. M. Moulton, Hase, M. C., Smith, K. M., and Iversen, P. L., “HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers.”, Antisense & nucleic acid drug development, vol. 13, no. 1, pp. 31-43, 2003.

Q. Wang, Yin, H., Camelliti, P., Betts, C., Moulton, H. M., Lee, H., Saleh, A. F., Gait, M. J., and Wood, M. J. A., “In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy.”, J Gene Med, vol. 12, no. 4, pp. 354-64, 2010.

Q. Wang, Yin, H., Camelliti, P., Betts, C., Moulton, H. M., Lee, H., Saleh, A. F., Gait, M. J., and Wood, M. J. A., “In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy.”, The journal of gene medicine, vol. 12, no. 4, pp. 354-64, 2010.

H. M. Moulton, “In vivo delivery of morpholino oligos by cell-penetrating peptides.”, Current pharmaceutical design, vol. 19, no. 16, pp. 2963-9, 2013.

H. M. Moulton, “In vivo delivery of morpholino oligos by cell-penetrating peptides.”, Curr Pharm Des, vol. 19, no. 16, pp. 2963-9, 2013.

G. McClorey, Fall, A. M., Moulton, H. M., Iversen, P. L., Rasko, J. E., Ryan, M., Fletcher, S., and Wilton, S. D., “Induced dystrophin exon skipping in human muscle explants.”, Neuromuscular disorders : NMD, vol. 16, no. 9-10, pp. 583-90, 2006.

B. W. Neuman, Stein, D. A., Kroeker, A. D., Moulton, H. M., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., “Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers.”, Advances in experimental medicine and biology, vol. 581, pp. 567-71, 2006.

B. W. Neuman, Stein, D. A., Kroeker, A. D., Churchill, M. J., Kim, A. M., Kuhn, P., Dawson, P., Moulton, H. M., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., “Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers.”, Journal of virology, vol. 79, no. 15, pp. 9665-76, 2005.

J. Yuan, Stein, D. A., Lim, T., Qiu, D., Coughlin, S., Liu, Z., Wang, Y., Blouch, R., Moulton, H. M., Iversen, P. L., and Yang, D., “Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site.”, Journal of virology, vol. 80, no. 23, pp. 11510-9, 2006.

T. S. Deas, Binduga-Gajewska, I., Tilgner, M., Ren, P., Stein, D. A., Moulton, H. M., Iversen, P. L., Kauffman, E. B., Kramer, L. D., and Shi, P. Y., “Inhibition of flavivirus infections by antisense oligomers specifically suppressing viral translation and RNA replication.”, J Virol, vol. 79, no. 8, pp. 4599-609, 2005.

B. L. Geller, Deere, J. D., Stein, D. A., Kroeker, A. D., Moulton, H. M., and Iversen, P. L., “Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers.”, Antimicrobial agents and chemotherapy, vol. 47, no. 10, pp. 3233-9, 2003.

M. Alonso, Stein, D. A., Thomann, E., Moulton, H. M., Leong, J. C., Iversen, P., and Mourich, D. V., “Inhibition of infectious haematopoietic necrosis virus in cell cultures with peptide-conjugated morpholino oligomers.”, Journal of fish diseases, vol. 28, no. 7, pp. 399-410, 2005.

Y. - J. Zhang, Wang, K. - Y., Stein, D. A., Patel, D., Watkins, R., Moulton, H. M., Iversen, P. L., and Matson, D. O., “Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers.”, Antiviral research, vol. 73, no. 1, pp. 12-23, 2007.

K. Rosenke, Leventhal, S., Moulton, H. M., Hatlevig, S., Hawman, D., Feldmann, H., and Stein, D. A., “Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers.”, J Antimicrob Chemother, vol. 76, no. 2, pp. 413-417, 2021.

K. Rosenke, Leventhal, S., Moulton, H. M., Hatlevig, S., Hawman, D., Feldmann, H., and Stein, D. A., “Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomers.”, bioRxiv, 2020.

N. Jearawiriyapaisarn, Moulton, H. M., Sazani, P., Kole, R., and Willis, M. S., “Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers.”, Cardiovascular research, vol. 85, no. 3, pp. 444-53, 2010.

N. Jearawiriyapaisarn, Moulton, H. M., Sazani, P., Kole, R., and Willis, M. S., “Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers.”, Cardiovasc Res, vol. 85, no. 3, pp. 444-53, 2010.

B. Wu, Lu, P., Cloer, C., Shaban, M., Grewal, S., Milazi, S., Shah, S. N., Moulton, H. M., and Lu, Q. Long, “Long-term rescue of dystrophin expression and improvement in muscle pathology and function in dystrophic mdx mice by peptide-conjugated morpholino.”, The American journal of pathology, vol. 181, no. 2, pp. 392-400, 2012.

B. Wu, Lu, P., Cloer, C., Shaban, M., Grewal, S., Milazi, S., Shah, S. N., Moulton, H. M., and Lu, Q. Long, “Long-term rescue of dystrophin expression and improvement in muscle pathology and function in dystrophic mdx mice by peptide-conjugated morpholino.”, Am J Pathol, vol. 181, no. 2, pp. 392-400, 2012.