Found 85 results
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E
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H. M., and Yin, H., Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 22, no. 7, pp. 1333-41, 2014.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H. M., and Yin, H., Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide-Morpholino Conjugate in Dystrophin-Deficient mdx Mice., Mol Ther, vol. 28, no. 10, pp. 2299-2301, 2020.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H. M., and Yin, H., Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice., Mol Ther, vol. 22, no. 7, pp. 1333-1341, 2014.
M. Nizzardo, Simone, C., Salani, S., Ruepp, M. - D., Rizzo, F., Ruggieri, M., Zanetta, C., Brajkovic, S., Moulton, H. M., Müehlemann, O., Bresolin, N., Comi, G. P., and Corti, S., Effect of combined systemic and local morpholino treatment on the spinal muscular atrophy Δ7 mouse model phenotype., Clinical therapeutics, vol. 36, no. 3, pp. 340-56.e5, 2014.
M. Nizzardo, Simone, C., Salani, S., Ruepp, M. - D., Rizzo, F., Ruggieri, M., Zanetta, C., Brajkovic, S., Moulton, H. M., Müehlemann, O., Bresolin, N., Comi, G. P., and Corti, S., Effect of combined systemic and local morpholino treatment on the spinal muscular atrophy Δ7 mouse model phenotype., Clin Ther, vol. 36, no. 3, pp. 340-56.e5, 2014.
D
S. Fletcher, Adams, A. M., Johnsen, R. D., Greer, K., Moulton, H. M., and Wilton, S. D., Dystrophin isoform induction in vivo by antisense-mediated alternative splicing., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 18, no. 6, pp. 1218-23, 2010.
S. Fletcher, Adams, A. M., Johnsen, R. D., Greer, K., Moulton, H. M., and Wilton, S. D., Dystrophin isoform induction in vivo by antisense-mediated alternative splicing., Mol Ther, vol. 18, no. 6, pp. 1218-23, 2010.
A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H. M., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., Diaphragm rescue alone prevents heart dysfunction in dystrophic mice., Human molecular genetics, vol. 20, no. 3, pp. 413-21, 2011.
A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H. M., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., Diaphragm rescue alone prevents heart dysfunction in dystrophic mice., Hum Mol Genet, vol. 20, no. 3, pp. 413-21, 2011.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M., and Buchmeier, M. J., Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors., Antimicrobial agents and chemotherapy, vol. 55, no. 10, pp. 4631-8, 2011.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M., and Buchmeier, M. J., Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors., Antimicrob Agents Chemother, vol. 55, no. 10, pp. 4631-8, 2011.
R. Abes, Moulton, H. M., Clair, P., Yang, S. - T., Abes, S., Melikov, K., Prevot, P., Youngblood, D. S., Iversen, P. L., Chernomordik, L. V., and Lebleu, B., Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies., Nucleic acids research, vol. 36, no. 20, pp. 6343-54, 2008.
C
J. D. Lykins, Filippova, E. V., Halavaty, A. S., Minasov, G., Zhou, Y., Dubrovska, I., Flores, K. J., Shuvalova, L. A., Ruan, J., Bissati, K. El, Dovgin, S., Roberts, C. W., Woods, S., Moulton, J. D., Moulton, H. M., McPhillie, M. J., Muench, S. P., Fishwick, C. W. G., Sabini, E., Shanmugam, D., Roos, D. S., McLeod, R., Anderson, W. F., and Ngô, H. M., CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in ., Front Cell Infect Microbiol, vol. 8, p. 352, 2018.
H. Yin, Moulton, H. M., Betts, C., and Wood, M., CPP-directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy., Methods in molecular biology (Clifton, N.J.), vol. 683, pp. 321-38, 2011.
H. Yin, Moulton, H. M., Betts, C., and Wood, M., CPP-directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy., Methods Mol Biol, vol. 683, pp. 321-38, 2011.
H. Yin, Boisguerin, P., Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Wang, Q., Walsh, A., Lebleu, B., and Wood, M. Ja, Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency., Mol Ther Nucleic Acids, vol. 2, p. e124, 2013.
H. Yin, Boisguerin, P., Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Wang, Q., Walsh, A., Lebleu, B., and Wood, M. J. A., Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency., Molecular therapy. Nucleic acids, vol. 2, p. e124, 2013.
F. Debart, Abes, S., Deglane, G., Moulton, H. M., Clair, P., Gait, M. J., Vasseur, J. - J., and Lebleu, B., Chemical modifications to improve the cellular uptake of oligonucleotides., Current topics in medicinal chemistry, vol. 7, no. 7, pp. 727-37, 2007.
D. L. Swenson, Warfield, K. L., Warren, T. K., Lovejoy, C., Hassinger, J. N., Ruthel, G., Blouch, R. E., Moulton, H. M., Weller, D. D., Iversen, P. L., and Bavari, S., Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection., Antimicrobial agents and chemotherapy, vol. 53, no. 5, pp. 2089-99, 2009.
H. M. Moulton, Nelson, M. H., Hatlevig, S. A., Reddy, M. T., and Iversen, P. L., Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides., Bioconjugate chemistry, vol. 15, no. 2, pp. 290-9, 2004.
R. Abes, Arzumanov, A. A., Moulton, H. M., Abes, S., Ivanova, G. D., Iversen, P. L., Gait, M. J., and Lebleu, B., Cell-penetrating-peptide-based delivery of oligonucleotides: an overview., Biochemical Society transactions, vol. 35, no. Pt 4, pp. 775-9, 2007.
H. M. Moulton, Cell-penetrating peptides enhance systemic delivery of antisense morpholino oligomers., Methods in molecular biology (Clifton, N.J.), vol. 867, pp. 407-14, 2012.
R. P. Wu, Youngblood, D. S., Hassinger, J. N., Lovejoy, C. E., Nelson, M. H., Iversen, P. L., and Moulton, H. M., Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity., Nucleic acids research, vol. 35, no. 15, pp. 5182-91, 2007.
H. M. Moulton, Fletcher, S., Neuman, B. W., McClorey, G., Stein, D. A., Abes, S., Wilton, S. D., Buchmeier, M. J., Lebleu, B., and Iversen, P. L., Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo., Biochemical Society transactions, vol. 35, no. Pt 4, pp. 826-8, 2007.
H. Yin, Moulton, H. M., Seow, Y., Boyd, C., Boutilier, J., Iverson, P., and Wood, M. J. A., Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function., Human molecular genetics, vol. 17, no. 24, pp. 3909-18, 2008.

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