Found 100 results
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E
Y. Echigoya, Trieu, N., Duddy, W., Moulton, H. M., Yin, H., Partridge, T. A., Hoffman, E. P., Kornegay, J. N., Rohret, F. A., Rogers, C. S., and Yokota, T., A Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping., Int J Mol Sci, vol. 22, no. 23, 2021.
B. Wu, Cloer, C., Lu, P., Milazi, S., Shaban, M., Shah, S. N., Marston-Poe, L., Moulton, H. M., and Lu, Q. L., Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice., Gene Ther, vol. 21, no. 9, pp. 785-93, 2014.
B. Wu, Cloer, C., Lu, P., Milazi, S., Shaban, M., Shah, S. N., Marston-Poe, L., Moulton, H. M., and Lu, Q. L., Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice., Gene therapy, vol. 21, no. 9, pp. 785-93, 2014.
L. Louis Seifert, Si, C., Saha, D., Sadic, M., de Vries, M., Ballentine, S., Briley, A., Wang, G., Valero-Jimenez, A. M., Mohamed, A., Schaefer, U., Moulton, H. M., García-Sastre, A., Tripathi, S., Rosenberg, B. R., and Dittmann, M., The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response., PLoS Pathog, vol. 15, no. 11, p. e1007634, 2019.
L. Cao, Han, G., Lin, C., Gu, B., Gao, X., Moulton, H. M., Seow, Y., and Yin, H., Erratum: Fructose Promotes Uptake and Activity of Oligonucleotides with Different Chemistries in a Context-Dependent Manner in Mice., Mol Ther Nucleic Acids, vol. 22, pp. 1040-1042, 2020.
Y. Dang, van Heusden, C., Nickerson, V., Chung, F., Wang, Y., Quinney, N. L., Gentzsch, M., Randell, S. H., Moulton, H. M., Kole, R., Ni, A., Juliano, R. L., and Kreda, S. M., Enhanced delivery of peptide-morpholino oligonucleotides with a small molecule to correct splicing defects in the lung., Nucleic Acids Res, vol. 49, no. 11, pp. 6100-6113, 2021.
Y. Echigoya, Nakamura, A., Nagata, T., Urasawa, N., Lim, K. Rowel Q., Trieu, N., Panesar, D., Kuraoka, M., Moulton, H. M., Saito, T., Aoki, Y., Iversen, P., Sazani, P., Kole, R., Maruyama, R., Partridge, T., Takeda, S. 'ichi, and Yokota, T., Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy., Proc Natl Acad Sci U S A, vol. 114, no. 16, pp. 4213-4218, 2017.
B. Wu, Moulton, H. M., Iversen, P. L., Jiang, J., Li, J., Li, J., Spurney, C. F., Sali, A., Guerron, A. D., Nagaraju, K., Doran, T., Lu, P., Xiao, X., and Lu, Q. Long, Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer., Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 39, pp. 14814-9, 2008.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H. M., and Yin, H., Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 22, no. 7, pp. 1333-41, 2014.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H. M., and Yin, H., Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide-Morpholino Conjugate in Dystrophin-Deficient mdx Mice., Mol Ther, vol. 28, no. 10, pp. 2299-2301, 2020.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H. M., and Yin, H., Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice., Mol Ther, vol. 22, no. 7, pp. 1333-1341, 2014.
M. Nizzardo, Simone, C., Salani, S., Ruepp, M. - D., Rizzo, F., Ruggieri, M., Zanetta, C., Brajkovic, S., Moulton, H. M., Müehlemann, O., Bresolin, N., Comi, G. P., and Corti, S., Effect of combined systemic and local morpholino treatment on the spinal muscular atrophy Δ7 mouse model phenotype., Clinical therapeutics, vol. 36, no. 3, pp. 340-56.e5, 2014.
M. Nizzardo, Simone, C., Salani, S., Ruepp, M. - D., Rizzo, F., Ruggieri, M., Zanetta, C., Brajkovic, S., Moulton, H. M., Müehlemann, O., Bresolin, N., Comi, G. P., and Corti, S., Effect of combined systemic and local morpholino treatment on the spinal muscular atrophy Δ7 mouse model phenotype., Clin Ther, vol. 36, no. 3, pp. 340-56.e5, 2014.
D
S. Fletcher, Adams, A. M., Johnsen, R. D., Greer, K., Moulton, H. M., and Wilton, S. D., Dystrophin isoform induction in vivo by antisense-mediated alternative splicing., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 18, no. 6, pp. 1218-23, 2010.
S. Fletcher, Adams, A. M., Johnsen, R. D., Greer, K., Moulton, H. M., and Wilton, S. D., Dystrophin isoform induction in vivo by antisense-mediated alternative splicing., Mol Ther, vol. 18, no. 6, pp. 1218-23, 2010.
A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H. M., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., Diaphragm rescue alone prevents heart dysfunction in dystrophic mice., Human molecular genetics, vol. 20, no. 3, pp. 413-21, 2011.
A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H. M., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., Diaphragm rescue alone prevents heart dysfunction in dystrophic mice., Hum Mol Genet, vol. 20, no. 3, pp. 413-21, 2011.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M., and Buchmeier, M. J., Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors., Antimicrob Agents Chemother, vol. 55, no. 10, pp. 4631-8, 2011.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M., and Buchmeier, M. J., Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors., Antimicrobial agents and chemotherapy, vol. 55, no. 10, pp. 4631-8, 2011.
R. Abes, Moulton, H. M., Clair, P., Yang, S. - T., Abes, S., Melikov, K., Prevot, P., Youngblood, D. S., Iversen, P. L., Chernomordik, L. V., and Lebleu, B., Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies., Nucleic acids research, vol. 36, no. 20, pp. 6343-54, 2008.

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