Found 19 results
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Journal Article
R. Rajsbaum, Versteeg, G. A., Schmid, S., Maestre, A. M., Belicha-Villanueva, A., Martínez-Romero, C., Patel, J. R., Morrison, J., Pisanelli, G., Miorin, L., Laurent-Rolle, M., Moulton, H. M., Stein, D. A., Fernandez-Sesma, A., tenOever, B. R., and García-Sastre, A., Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response., Immunity, vol. 40, no. 6, pp. 880-95, 2014.
R. Rajsbaum, Versteeg, G. A., Schmid, S., Maestre, A. M., Belicha-Villanueva, A., Martínez-Romero, C., Patel, J. R., Morrison, J., Pisanelli, G., Miorin, L., Laurent-Rolle, M., Moulton, H. M., Stein, D. A., Fernandez-Sesma, A., tenOever, B. R., and García-Sastre, A., Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response., Immunity, vol. 40, no. 6, pp. 880-95, 2014.
H. Limburg, Harbig, A., Bestle, D., Stein, D. A., Moulton, H. M., Jaeger, J., Janga, H., Hardes, K., Koepke, J., Schulte, L., Koczulla, A. Rembert, Schmeck, B., Klenk, H. - D., and Böttcher-Friebertshäuser, E., TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes., J Virol, vol. 93, no. 21, 2019.
D. Bestle, Heindl, M. Ruth, Limburg, H., van, T. Van Lam, Pilgram, O., Moulton, H. M., Stein, D. A., Hardes, K., Eickmann, M., Dolnik, O., Rohde, C., Klenk, H. - D., Garten, W., Steinmetzer, T., and Böttcher-Friebertshäuser, E., TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells., Life Sci Alliance, vol. 3, no. 9, 2020.
S. Soonthornvacharin, Rodriguez-Frandsen, A., Zhou, Y., Galvez, F., Huffmaster, N. J., Tripathi, S., Balasubramaniam, V. R. M. T., Inoue, A., de Castro, E., Moulton, H. M., Stein, D. A., Sánchez-Aparicio, M. Teresa, De Jesus, P. D., Nguyen, Q., König, R., Krogan, N. J., García-Sastre, A., Yoh, S. M., and Chanda, S. K., Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation., Nat Microbiol, vol. 2, p. 17022, 2017.
S. Tripathi, Pohl, M. O., Zhou, Y., Rodriguez-Frandsen, A., Wang, G., Stein, D. A., Moulton, H. M., DeJesus, P., Che, J., Mulder, L. C. F., Yángüez, E., Andenmatten, D., Pache, L., Manicassamy, B., Albrecht, R. A., Gonzalez, M. G., Nguyen, Q., Brass, A., Elledge, S., White, M., Shapira, S., Hacohen, N., Karlas, A., Meyer, T. F., Shales, M., Gatorano, A., Johnson, J. R., Jang, G., Johnson, T., Verschueren, E., Sanders, D., Krogan, N., Shaw, M., König, R., Stertz, S., García-Sastre, A., and Chanda, S. K., Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding., Cell Host Microbe, vol. 18, no. 6, pp. 723-35, 2015.
K. Rosenke, Leventhal, S., Moulton, H. M., Hatlevig, S., Hawman, D., Feldmann, H., and Stein, D. A., Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomers., bioRxiv, 2020.
Y. - J. Zhang, Wang, K. - Y., Stein, D. A., Patel, D., Watkins, R., Moulton, H. M., Iversen, P. L., and Matson, D. O., Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers., Antiviral research, vol. 73, no. 1, pp. 12-23, 2007.
Q. Ge, Pastey, M., Kobasa, D., Puthavathana, P., Lupfer, C., Bestwick, R. K., Iversen, P. L., Chen, J., and Stein, D. A., Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers., Antimicrobial agents and chemotherapy, vol. 50, no. 11, pp. 3724-33, 2006.
C. Lupfer, Stein, D. A., Mourich, D. V., Tepper, S. E., Iversen, P. L., and Pastey, M., Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers., Archives of virology, vol. 153, no. 5, pp. 929-37, 2008.
J. Yuan, Stein, D. A., Lim, T., Qiu, D., Coughlin, S., Liu, Z., Wang, Y., Blouch, R., Moulton, H. M., Iversen, P. L., and Yang, D., Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site., Journal of virology, vol. 80, no. 23, pp. 11510-9, 2006.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Churchill, M. J., Kim, A. M., Kuhn, P., Dawson, P., Moulton, H. M., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers., Journal of virology, vol. 79, no. 15, pp. 9665-76, 2005.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Moulton, H. M., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers., Advances in experimental medicine and biology, vol. 581, pp. 567-71, 2006.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M., and Buchmeier, M. J., Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors., Antimicrob Agents Chemother, vol. 55, no. 10, pp. 4631-8, 2011.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M., and Buchmeier, M. J., Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors., Antimicrobial agents and chemotherapy, vol. 55, no. 10, pp. 4631-8, 2011.
B. Lebleu, Moulton, H. M., Abes, R., Ivanova, G. D., Abes, S., Stein, D. A., Iversen, P. L., Arzumanov, A. A., and Gait, M. J., Cell penetrating peptide conjugates of steric block oligonucleotides., Advanced drug delivery reviews, vol. 60, no. 4-5, pp. 517-29, 2008.
M. H. Nelson, Stein, D. A., Kroeker, A. D., Hatlevig, S. A., Iversen, P. L., and Moulton, H. M., Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity., Bioconjugate chemistry, vol. 16, no. 4, pp. 959-66, 2005.
R. Burrer, Neuman, B. W., Ting, J. P. C., Stein, D. A., Moulton, H. M., Iversen, P. L., Kuhn, P., and Buchmeier, M. J., Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models., Journal of virology, vol. 81, no. 11, pp. 5637-48, 2007.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Paulino, A. D., Moulton, H. M., Iversen, P. L., and Buchmeier, M. J., Antisense morpholino-oligomers directed against the 5' end of the genome inhibit coronavirus proliferation and growth., Journal of virology, vol. 78, no. 11, pp. 5891-9, 2004.