Found 86 results
Author Title Type [ Year(Asc)]
Filters: Author is Hong M Moulton  [Clear All Filters]
2009
H. Moulton, Wu, B., Jearawiriyapaisarn, N., Sazani, P., Lu, Q. Long, and Kole, R., Peptide-morpholino conjugate: a promising therapeutic for Duchenne muscular dystrophy., Annals of the New York Academy of Sciences, vol. 1175, pp. 55-60, 2009.
S. Svasti, Suwanmanee, T., Fucharoen, S., Moulton, H., Nelson, M. H., Maeda, N., Smithies, O., and Kole, R., RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice., Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 4, pp. 1205-10, 2009.
2008
R. Abes, Arzumanov, A., Moulton, H., Abes, S., Ivanova, G., Gait, M. J., Iversen, P., and Lebleu, B., Arginine-rich cell penetrating peptides: design, structure-activity, and applications to alter pre-mRNA splicing by steric-block oligonucleotides., Journal of peptide science : an official publication of the European Peptide Society, vol. 14, no. 4, pp. 455-60, 2008.
B. Lebleu, Moulton, H., Abes, R., Ivanova, G. D., Abes, S., Stein, D. A., Iversen, P. L., Arzumanov, A. A., and Gait, M. J., Cell penetrating peptide conjugates of steric block oligonucleotides., Advanced drug delivery reviews, vol. 60, no. 4-5, pp. 517-29, 2008.
H. Yin, Moulton, H., Seow, Y., Boyd, C., Boutilier, J., Iverson, P., and Wood, M. J. A., Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function., Human molecular genetics, vol. 17, no. 24, pp. 3909-18, 2008.
R. Abes, Moulton, H., Clair, P., Yang, S. - T., Abes, S., Melikov, K., Prevot, P., Youngblood, D. S., Iversen, P. L., Chernomordik, L. V., and Lebleu, B., Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies., Nucleic acids research, vol. 36, no. 20, pp. 6343-54, 2008.
B. Wu, Moulton, H., Iversen, P. L., Jiang, J., Li, J., Li, J., Spurney, C. F., Sali, A., Guerron, A. D., Nagaraju, K., Doran, T., Lu, P., Xiao, X., and Lu, Q. Long, Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer., Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 39, pp. 14814-9, 2008.
N. Jearawiriyapaisarn, Moulton, H., Buckley, B., Roberts, J., Sazani, P., Fucharoen, S., Iversen, P. L., and Kole, R., Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 16, no. 9, pp. 1624-9, 2008.
2007
R. Burrer, Neuman, B. W., Ting, J. P. C., Stein, D. A., Moulton, H., Iversen, P. L., Kuhn, P., and Buchmeier, M. J., Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models., Journal of virology, vol. 81, no. 11, pp. 5637-48, 2007.
N. B. Marshall, Oda, S. K., London, C. A., Moulton, H., Iversen, P. L., Kerkvliet, N. I., and Mourich, D. V., Arginine-rich cell-penetrating peptides facilitate delivery of antisense oligomers into murine leukocytes and alter pre-mRNA splicing., Journal of immunological methods, vol. 325, no. 1-2, pp. 114-26, 2007.
H. Moulton, Fletcher, S., Neuman, B. W., McClorey, G., Stein, D. A., Abes, S., Wilton, S. D., Buchmeier, M. J., Lebleu, B., and Iversen, P. L., Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo., Biochemical Society transactions, vol. 35, no. Pt 4, pp. 826-8, 2007.
R. P. Wu, Youngblood, D. S., Hassinger, J. N., Lovejoy, C. E., Nelson, M. H., Iversen, P. L., and Moulton, H., Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity., Nucleic acids research, vol. 35, no. 15, pp. 5182-91, 2007.
R. Abes, Arzumanov, A. A., Moulton, H., Abes, S., Ivanova, G. D., Iversen, P. L., Gait, M. J., and Lebleu, B., Cell-penetrating-peptide-based delivery of oligonucleotides: an overview., Biochemical Society transactions, vol. 35, no. Pt 4, pp. 775-9, 2007.
F. Debart, Abes, S., Deglane, G., Moulton, H., Clair, P., Gait, M. J., Vasseur, J. - J., and Lebleu, B., Chemical modifications to improve the cellular uptake of oligonucleotides., Current topics in medicinal chemistry, vol. 7, no. 7, pp. 727-37, 2007.
Y. - J. Zhang, Wang, K. - Y., Stein, D. A., Patel, D., Watkins, R., Moulton, H., Iversen, P. L., and Matson, D. O., Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers., Antiviral research, vol. 73, no. 1, pp. 12-23, 2007.
S. Fletcher, Honeyman, K., Fall, A. M., Harding, P. L., Johnsen, R. D., Steinhaus, J. P., Moulton, H., Iversen, P. L., and Wilton, S. D., Morpholino oligomer-mediated exon skipping averts the onset of dystrophic pathology in the mdx mouse., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 15, no. 9, pp. 1587-92, 2007.
S. Abes, Moulton, H., Turner, J., Clair, P., Richard, J. P., Iversen, P., Gait, M. J., and Lebleu, B., Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides., Biochemical Society transactions, vol. 35, no. Pt 1, pp. 53-5, 2007.
A. Amantana, Moulton, H., Cate, M. L., Reddy, M. T., Whitehead, T., Hassinger, J. N., Youngblood, D. S., and Iversen, P. L., Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate., Bioconjugate chemistry, vol. 18, no. 4, pp. 1325-31, 2007.
D. S. Youngblood, Hatlevig, S. A., Hassinger, J. N., Iversen, P. L., and Moulton, H., Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells., Bioconjugate chemistry, vol. 18, no. 1, pp. 50-60, 2007.

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