Found 23 results
Author Title Type [ Year(Asc)]
Filters: Author is Iversen, Patrick L  [Clear All Filters]
2009
D. L. Swenson, Warfield, K. L., Warren, T. K., Lovejoy, C., Hassinger, J. N., Ruthel, G., Blouch, R. E., Moulton, H. M., Weller, D. D., Iversen, P. L., and Bavari, S., “Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection.”, Antimicrobial agents and chemotherapy, vol. 53, no. 5, pp. 2089-99, 2009.
2008
B. Lebleu, Moulton, H. M., Abes, R., Ivanova, G. D., Abes, S., Stein, D. A., Iversen, P. L., Arzumanov, A. A., and Gait, M. J., “Cell penetrating peptide conjugates of steric block oligonucleotides.”, Advanced drug delivery reviews, vol. 60, no. 4-5, pp. 517-29, 2008.
R. Abes, Moulton, H. M., Clair, P., Yang, S. - T., Abes, S., Melikov, K., Prevot, P., Youngblood, D. S., Iversen, P. L., Chernomordik, L. V., and Lebleu, B., “Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies.”, Nucleic acids research, vol. 36, no. 20, pp. 6343-54, 2008.
B. Wu, Moulton, H. M., Iversen, P. L., Jiang, J., Li, J., Li, J., Spurney, C. F., Sali, A., Guerron, A. D., Nagaraju, K., Doran, T., Lu, P., Xiao, X., and Lu, Q. Long, “Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer.”, Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 39, pp. 14814-9, 2008.
C. Lupfer, Stein, D. A., Mourich, D. V., Tepper, S. E., Iversen, P. L., and Pastey, M., “Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers.”, Archives of virology, vol. 153, no. 5, pp. 929-37, 2008.
N. Jearawiriyapaisarn, Moulton, H. M., Buckley, B., Roberts, J., Sazani, P., Fucharoen, S., Iversen, P. L., and Kole, R., “Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.”, Molecular therapy : the journal of the American Society of Gene Therapy, vol. 16, no. 9, pp. 1624-9, 2008.
2007
R. Burrer, Neuman, B. W., Ting, J. P. C., Stein, D. A., Moulton, H. M., Iversen, P. L., Kuhn, P., and Buchmeier, M. J., “Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models.”, Journal of virology, vol. 81, no. 11, pp. 5637-48, 2007.
R. P. Wu, Youngblood, D. S., Hassinger, J. N., Lovejoy, C. E., Nelson, M. H., Iversen, P. L., and Moulton, H. M., “Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity.”, Nucleic acids research, vol. 35, no. 15, pp. 5182-91, 2007.
Y. - J. Zhang, Wang, K. - Y., Stein, D. A., Patel, D., Watkins, R., Moulton, H. M., Iversen, P. L., and Matson, D. O., “Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers.”, Antiviral research, vol. 73, no. 1, pp. 12-23, 2007.
S. Fletcher, Honeyman, K., Fall, A. M., Harding, P. L., Johnsen, R. D., Steinhaus, J. P., Moulton, H. M., Iversen, P. L., and Wilton, S. D., “Morpholino oligomer-mediated exon skipping averts the onset of dystrophic pathology in the mdx mouse.”, Molecular therapy : the journal of the American Society of Gene Therapy, vol. 15, no. 9, pp. 1587-92, 2007.
A. Amantana, Moulton, H. M., Cate, M. L., Reddy, M. T., Whitehead, T., Hassinger, J. N., Youngblood, D. S., and Iversen, P. L., “Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate.”, Bioconjugate chemistry, vol. 18, no. 4, pp. 1325-31, 2007.
D. S. Youngblood, Hatlevig, S. A., Hassinger, J. N., Iversen, P. L., and Moulton, H. M., “Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells.”, Bioconjugate chemistry, vol. 18, no. 1, pp. 50-60, 2007.
2006
B. W. Neuman, Stein, D. A., Kroeker, A. D., Moulton, H. M., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., “Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers.”, Advances in experimental medicine and biology, vol. 581, pp. 567-71, 2006.
J. Yuan, Stein, D. A., Lim, T., Qiu, D., Coughlin, S., Liu, Z., Wang, Y., Blouch, R., Moulton, H. M., Iversen, P. L., and Yang, D., “Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site.”, Journal of virology, vol. 80, no. 23, pp. 11510-9, 2006.
Q. Ge, Pastey, M., Kobasa, D., Puthavathana, P., Lupfer, C., Bestwick, R. K., Iversen, P. L., Chen, J., and Stein, D. A., “Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers.”, Antimicrobial agents and chemotherapy, vol. 50, no. 11, pp. 3724-33, 2006.
S. Abes, Moulton, H. M., Clair, P., Prevot, P., Youngblood, D. S., Wu, R. P., Iversen, P. L., and Lebleu, B., “Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.”, Journal of controlled release : official journal of the Controlled Release Society, vol. 116, no. 3, pp. 304-13, 2006.
2005
M. H. Nelson, Stein, D. A., Kroeker, A. D., Hatlevig, S. A., Iversen, P. L., and Moulton, H. M., “Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity.”, Bioconjugate chemistry, vol. 16, no. 4, pp. 959-66, 2005.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Churchill, M. J., Kim, A. M., Kuhn, P., Dawson, P., Moulton, H. M., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., “Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers.”, Journal of virology, vol. 79, no. 15, pp. 9665-76, 2005.
2004
B. W. Neuman, Stein, D. A., Kroeker, A. D., Paulino, A. D., Moulton, H. M., Iversen, P. L., and Buchmeier, M. J., “Antisense morpholino-oligomers directed against the 5' end of the genome inhibit coronavirus proliferation and growth.”, Journal of virology, vol. 78, no. 11, pp. 5891-9, 2004.
H. M. Moulton, Nelson, M. H., Hatlevig, S. A., Reddy, M. T., and Iversen, P. L., “Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides.”, Bioconjugate chemistry, vol. 15, no. 2, pp. 290-9, 2004.
2003
H. M. Moulton, Hase, M. C., Smith, K. M., and Iversen, P. L., “HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers.”, Antisense & nucleic acid drug development, vol. 13, no. 1, pp. 31-43, 2003.
P. L. Iversen, Mourich, D. V., and Moulton, H. M., “Monoclonal antibodies to two epitopes of beta-human chorionic gonadotropin for the treatment of cancer.”, Current opinion in molecular therapeutics, vol. 5, no. 2, pp. 156-60, 2003.
2002
H. M. Moulton, Yoshihara, P. H., Mason, D. H., Iversen, P. L., and Triozzi, P. L., “Active specific immunotherapy with a beta-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: antibody response is associated with improved survival.”, Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 8, no. 7, pp. 2044-51, 2002.