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Home
Publications
Found 23 results
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Iversen, Patrick L
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V
S. Abes
,
Moulton, H. M.
,
Clair, P.
,
Prevot, P.
,
Youngblood, D. S.
,
Wu, R. P.
,
Iversen, P. L.
, and
Lebleu, B.
,
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Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.
”
,
Journal of controlled release : official journal of the Controlled Release Society
, vol. 116, no. 3, pp. 304-13, 2006.
S
N. Jearawiriyapaisarn
,
Moulton, H. M.
,
Buckley, B.
,
Roberts, J.
,
Sazani, P.
,
Fucharoen, S.
,
Iversen, P. L.
, and
Kole, R.
,
“
Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.
”
,
Molecular therapy : the journal of the American Society of Gene Therapy
, vol. 16, no. 9, pp. 1624-9, 2008.
D. S. Youngblood
,
Hatlevig, S. A.
,
Hassinger, J. N.
,
Iversen, P. L.
, and
Moulton, H. M.
,
“
Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells.
”
,
Bioconjugate chemistry
, vol. 18, no. 1, pp. 50-60, 2007.
P
A. Amantana
,
Moulton, H. M.
,
Cate, M. L.
,
Reddy, M. T.
,
Whitehead, T.
,
Hassinger, J. N.
,
Youngblood, D. S.
, and
Iversen, P. L.
,
“
Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate.
”
,
Bioconjugate chemistry
, vol. 18, no. 4, pp. 1325-31, 2007.
M
S. Fletcher
,
Honeyman, K.
,
Fall, A. M.
,
Harding, P. L.
,
Johnsen, R. D.
,
Steinhaus, J. P.
,
Moulton, H. M.
,
Iversen, P. L.
, and
Wilton, S. D.
,
“
Morpholino oligomer-mediated exon skipping averts the onset of dystrophic pathology in the mdx mouse.
”
,
Molecular therapy : the journal of the American Society of Gene Therapy
, vol. 15, no. 9, pp. 1587-92, 2007.
P. L. Iversen
,
Mourich, D. V.
, and
Moulton, H. M.
,
“
Monoclonal antibodies to two epitopes of beta-human chorionic gonadotropin for the treatment of cancer.
”
,
Current opinion in molecular therapeutics
, vol. 5, no. 2, pp. 156-60, 2003.
I
Y. - J. Zhang
,
Wang, K. - Y.
,
Stein, D. A.
,
Patel, D.
,
Watkins, R.
,
Moulton, H. M.
,
Iversen, P. L.
, and
Matson, D. O.
,
“
Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers.
”
,
Antiviral research
, vol. 73, no. 1, pp. 12-23, 2007.
Q. Ge
,
Pastey, M.
,
Kobasa, D.
,
Puthavathana, P.
,
Lupfer, C.
,
Bestwick, R. K.
,
Iversen, P. L.
,
Chen, J.
, and
Stein, D. A.
,
“
Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers.
”
,
Antimicrobial agents and chemotherapy
, vol. 50, no. 11, pp. 3724-33, 2006.
C. Lupfer
,
Stein, D. A.
,
Mourich, D. V.
,
Tepper, S. E.
,
Iversen, P. L.
, and
Pastey, M.
,
“
Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers.
”
,
Archives of virology
, vol. 153, no. 5, pp. 929-37, 2008.
J. Yuan
,
Stein, D. A.
,
Lim, T.
,
Qiu, D.
,
Coughlin, S.
,
Liu, Z.
,
Wang, Y.
,
Blouch, R.
,
Moulton, H. M.
,
Iversen, P. L.
, and
Yang, D.
,
“
Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site.
”
,
Journal of virology
, vol. 80, no. 23, pp. 11510-9, 2006.
B. W. Neuman
,
Stein, D. A.
,
Kroeker, A. D.
,
Churchill, M. J.
,
Kim, A. M.
,
Kuhn, P.
,
Dawson, P.
,
Moulton, H. M.
,
Bestwick, R. K.
,
Iversen, P. L.
, and
Buchmeier, M. J.
,
“
Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers.
”
,
Journal of virology
, vol. 79, no. 15, pp. 9665-76, 2005.
B. W. Neuman
,
Stein, D. A.
,
Kroeker, A. D.
,
Moulton, H. M.
,
Bestwick, R. K.
,
Iversen, P. L.
, and
Buchmeier, M. J.
,
“
Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers.
”
,
Advances in experimental medicine and biology
, vol. 581, pp. 567-71, 2006.
H
H. M. Moulton
,
Hase, M. C.
,
Smith, K. M.
, and
Iversen, P. L.
,
“
HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers.
”
,
Antisense & nucleic acid drug development
, vol. 13, no. 1, pp. 31-43, 2003.
E
B. Wu
,
Moulton, H. M.
,
Iversen, P. L.
,
Jiang, J.
,
Li, J.
,
Li, J.
,
Spurney, C. F.
,
Sali, A.
,
Guerron, A. D.
,
Nagaraju, K.
,
Doran, T.
,
Lu, P.
,
Xiao, X.
, and
Lu, Q. Long
,
“
Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer.
”
,
Proceedings of the National Academy of Sciences of the United States of America
, vol. 105, no. 39, pp. 14814-9, 2008.
D
R. Abes
,
Moulton, H. M.
,
Clair, P.
,
Yang, S. - T.
,
Abes, S.
,
Melikov, K.
,
Prevot, P.
,
Youngblood, D. S.
,
Iversen, P. L.
,
Chernomordik, L. V.
, and
Lebleu, B.
,
“
Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies.
”
,
Nucleic acids research
, vol. 36, no. 20, pp. 6343-54, 2008.
C
D. L. Swenson
,
Warfield, K. L.
,
Warren, T. K.
,
Lovejoy, C.
,
Hassinger, J. N.
,
Ruthel, G.
,
Blouch, R. E.
,
Moulton, H. M.
,
Weller, D. D.
,
Iversen, P. L.
, and
Bavari, S.
,
“
Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection.
”
,
Antimicrobial agents and chemotherapy
, vol. 53, no. 5, pp. 2089-99, 2009.
H. M. Moulton
,
Nelson, M. H.
,
Hatlevig, S. A.
,
Reddy, M. T.
, and
Iversen, P. L.
,
“
Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides.
”
,
Bioconjugate chemistry
, vol. 15, no. 2, pp. 290-9, 2004.
R. P. Wu
,
Youngblood, D. S.
,
Hassinger, J. N.
,
Lovejoy, C. E.
,
Nelson, M. H.
,
Iversen, P. L.
, and
Moulton, H. M.
,
“
Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity.
”
,
Nucleic acids research
, vol. 35, no. 15, pp. 5182-91, 2007.
B. Lebleu
,
Moulton, H. M.
,
Abes, R.
,
Ivanova, G. D.
,
Abes, S.
,
Stein, D. A.
,
Iversen, P. L.
,
Arzumanov, A. A.
, and
Gait, M. J.
,
“
Cell penetrating peptide conjugates of steric block oligonucleotides.
”
,
Advanced drug delivery reviews
, vol. 60, no. 4-5, pp. 517-29, 2008.
A
M. H. Nelson
,
Stein, D. A.
,
Kroeker, A. D.
,
Hatlevig, S. A.
,
Iversen, P. L.
, and
Moulton, H. M.
,
“
Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity.
”
,
Bioconjugate chemistry
, vol. 16, no. 4, pp. 959-66, 2005.
R. Burrer
,
Neuman, B. W.
,
Ting, J. P. C.
,
Stein, D. A.
,
Moulton, H. M.
,
Iversen, P. L.
,
Kuhn, P.
, and
Buchmeier, M. J.
,
“
Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models.
”
,
Journal of virology
, vol. 81, no. 11, pp. 5637-48, 2007.
B. W. Neuman
,
Stein, D. A.
,
Kroeker, A. D.
,
Paulino, A. D.
,
Moulton, H. M.
,
Iversen, P. L.
, and
Buchmeier, M. J.
,
“
Antisense morpholino-oligomers directed against the 5' end of the genome inhibit coronavirus proliferation and growth.
”
,
Journal of virology
, vol. 78, no. 11, pp. 5891-9, 2004.
H. M. Moulton
,
Yoshihara, P. H.
,
Mason, D. H.
,
Iversen, P. L.
, and
Triozzi, P. L.
,
“
Active specific immunotherapy with a beta-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: antibody response is associated with improved survival.
”
,
Clinical cancer research : an official journal of the American Association for Cancer Research
, vol. 8, no. 7, pp. 2044-51, 2002.
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