Found 19 results
Author Title [ Type(Desc)] Year
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Journal Article
B. W. Neuman, Stein, D. A., Kroeker, A. D., Paulino, A. D., Moulton, H., Iversen, P. L., and Buchmeier, M. J., Antisense morpholino-oligomers directed against the 5' end of the genome inhibit coronavirus proliferation and growth., Journal of virology, vol. 78, no. 11, pp. 5891-9, 2004.
R. Burrer, Neuman, B. W., Ting, J. P. C., Stein, D. A., Moulton, H., Iversen, P. L., Kuhn, P., and Buchmeier, M. J., Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models., Journal of virology, vol. 81, no. 11, pp. 5637-48, 2007.
M. H. Nelson, Stein, D. A., Kroeker, A. D., Hatlevig, S. A., Iversen, P. L., and Moulton, H., Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity., Bioconjugate chemistry, vol. 16, no. 4, pp. 959-66, 2005.
B. Lebleu, Moulton, H., Abes, R., Ivanova, G. D., Abes, S., Stein, D. A., Iversen, P. L., Arzumanov, A. A., and Gait, M. J., Cell penetrating peptide conjugates of steric block oligonucleotides., Advanced drug delivery reviews, vol. 60, no. 4-5, pp. 517-29, 2008.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H., and Buchmeier, M. J., Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors., Antimicrobial agents and chemotherapy, vol. 55, no. 10, pp. 4631-8, 2011.
B. W. Neuman, Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H., and Buchmeier, M. J., Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors., Antimicrob Agents Chemother, vol. 55, no. 10, pp. 4631-8, 2011.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Moulton, H., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers., Advances in experimental medicine and biology, vol. 581, pp. 567-71, 2006.
B. W. Neuman, Stein, D. A., Kroeker, A. D., Churchill, M. J., Kim, A. M., Kuhn, P., Dawson, P., Moulton, H., Bestwick, R. K., Iversen, P. L., and Buchmeier, M. J., Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers., Journal of virology, vol. 79, no. 15, pp. 9665-76, 2005.
J. Yuan, Stein, D. A., Lim, T., Qiu, D., Coughlin, S., Liu, Z., Wang, Y., Blouch, R., Moulton, H., Iversen, P. L., and Yang, D., Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site., Journal of virology, vol. 80, no. 23, pp. 11510-9, 2006.
C. Lupfer, Stein, D. A., Mourich, D. V., Tepper, S. E., Iversen, P. L., and Pastey, M., Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers., Archives of virology, vol. 153, no. 5, pp. 929-37, 2008.
Q. Ge, Pastey, M., Kobasa, D., Puthavathana, P., Lupfer, C., Bestwick, R. K., Iversen, P. L., Chen, J., and Stein, D. A., Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers., Antimicrobial agents and chemotherapy, vol. 50, no. 11, pp. 3724-33, 2006.
Y. - J. Zhang, Wang, K. - Y., Stein, D. A., Patel, D., Watkins, R., Moulton, H., Iversen, P. L., and Matson, D. O., Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers., Antiviral research, vol. 73, no. 1, pp. 12-23, 2007.
K. Rosenke, Leventhal, S., Moulton, H., Hatlevig, S., Hawman, D., Feldmann, H., and Stein, D. A., Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomers., bioRxiv, 2020.
S. Tripathi, Pohl, M. O., Zhou, Y., Rodriguez-Frandsen, A., Wang, G., Stein, D. A., Moulton, H., DeJesus, P., Che, J., Mulder, L. C. F., Yángüez, E., Andenmatten, D., Pache, L., Manicassamy, B., Albrecht, R. A., Gonzalez, M. G., Nguyen, Q., Brass, A., Elledge, S., White, M., Shapira, S., Hacohen, N., Karlas, A., Meyer, T. F., Shales, M., Gatorano, A., Johnson, J. R., Jang, G., Johnson, T., Verschueren, E., Sanders, D., Krogan, N., Shaw, M., König, R., Stertz, S., García-Sastre, A., and Chanda, S. K., Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding., Cell Host Microbe, vol. 18, no. 6, pp. 723-35, 2015.
S. Soonthornvacharin, Rodriguez-Frandsen, A., Zhou, Y., Galvez, F., Huffmaster, N. J., Tripathi, S., Balasubramaniam, V. R. M. T., Inoue, A., de Castro, E., Moulton, H., Stein, D. A., Sánchez-Aparicio, M. Teresa, De Jesus, P. D., Nguyen, Q., König, R., Krogan, N. J., García-Sastre, A., Yoh, S. M., and Chanda, S. K., Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation., Nat Microbiol, vol. 2, p. 17022, 2017.
D. Bestle, Heindl, M. Ruth, Limburg, H., van, T. Van Lam, Pilgram, O., Moulton, H., Stein, D. A., Hardes, K., Eickmann, M., Dolnik, O., Rohde, C., Klenk, H. - D., Garten, W., Steinmetzer, T., and Böttcher-Friebertshäuser, E., TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells., Life Sci Alliance, vol. 3, no. 9, 2020.
H. Limburg, Harbig, A., Bestle, D., Stein, D. A., Moulton, H., Jaeger, J., Janga, H., Hardes, K., Koepke, J., Schulte, L., Koczulla, A. Rembert, Schmeck, B., Klenk, H. - D., and Böttcher-Friebertshäuser, E., TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes., J Virol, vol. 93, no. 21, 2019.
R. Rajsbaum, Versteeg, G. A., Schmid, S., Maestre, A. M., Belicha-Villanueva, A., Martínez-Romero, C., Patel, J. R., Morrison, J., Pisanelli, G., Miorin, L., Laurent-Rolle, M., Moulton, H., Stein, D. A., Fernandez-Sesma, A., tenOever, B. R., and García-Sastre, A., Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response., Immunity, vol. 40, no. 6, pp. 880-95, 2014.
R. Rajsbaum, Versteeg, G. A., Schmid, S., Maestre, A. M., Belicha-Villanueva, A., Martínez-Romero, C., Patel, J. R., Morrison, J., Pisanelli, G., Miorin, L., Laurent-Rolle, M., Moulton, H., Stein, D. A., Fernandez-Sesma, A., tenOever, B. R., and García-Sastre, A., Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response., Immunity, vol. 40, no. 6, pp. 880-95, 2014.