Found 86 results
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Journal Article
J. L. Sanders, Zhou, Y., Moulton, H., Moulton, Z. X., McLeod, R., Dubey, J. P., Weiss, L. M., and Kent, M. L., The zebrafish, Danio rerio, as a model for Toxoplasma gondii: an initial description of infection in fish., J Fish Dis, vol. 38, no. 7, pp. 675-9, 2015.
J. L. Sanders, Zhou, Y., Moulton, H., Moulton, Z. X., McLeod, R., Dubey, J. P., Weiss, L. M., and Kent, M. L., The zebrafish, Danio rerio, as a model for Toxoplasma gondii: an initial description of infection in fish., Journal of fish diseases, vol. 38, no. 7, pp. 675-9, 2015.
S. Abes, Moulton, H., Clair, P., Prevot, P., Youngblood, D. S., Wu, R. P., Iversen, P. L., and Lebleu, B., Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents., Journal of controlled release : official journal of the Controlled Release Society, vol. 116, no. 3, pp. 304-13, 2006.
R. Rajsbaum, Versteeg, G. A., Schmid, S., Maestre, A. M., Belicha-Villanueva, A., Martínez-Romero, C., Patel, J. R., Morrison, J., Pisanelli, G., Miorin, L., Laurent-Rolle, M., Moulton, H., Stein, D. A., Fernandez-Sesma, A., tenOever, B. R., and García-Sastre, A., Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response., Immunity, vol. 40, no. 6, pp. 880-95, 2014.
R. Rajsbaum, Versteeg, G. A., Schmid, S., Maestre, A. M., Belicha-Villanueva, A., Martínez-Romero, C., Patel, J. R., Morrison, J., Pisanelli, G., Miorin, L., Laurent-Rolle, M., Moulton, H., Stein, D. A., Fernandez-Sesma, A., tenOever, B. R., and García-Sastre, A., Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response., Immunity, vol. 40, no. 6, pp. 880-95, 2014.
H. Limburg, Harbig, A., Bestle, D., Stein, D. A., Moulton, H., Jaeger, J., Janga, H., Hardes, K., Koepke, J., Schulte, L., Koczulla, A. Rembert, Schmeck, B., Klenk, H. - D., and Böttcher-Friebertshäuser, E., TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes., J Virol, vol. 93, no. 21, 2019.
D. Bestle, Heindl, M. Ruth, Limburg, H., van, T. Van Lam, Pilgram, O., Moulton, H., Stein, D. A., Hardes, K., Eickmann, M., Dolnik, O., Rohde, C., Klenk, H. - D., Garten, W., Steinmetzer, T., and Böttcher-Friebertshäuser, E., TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells., Life Sci Alliance, vol. 3, no. 9, 2020.
S. Soonthornvacharin, Rodriguez-Frandsen, A., Zhou, Y., Galvez, F., Huffmaster, N. J., Tripathi, S., Balasubramaniam, V. R. M. T., Inoue, A., de Castro, E., Moulton, H., Stein, D. A., Sánchez-Aparicio, M. Teresa, De Jesus, P. D., Nguyen, Q., König, R., Krogan, N. J., García-Sastre, A., Yoh, S. M., and Chanda, S. K., Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation., Nat Microbiol, vol. 2, p. 17022, 2017.
N. Jearawiriyapaisarn, Moulton, H., Buckley, B., Roberts, J., Sazani, P., Fucharoen, S., Iversen, P. L., and Kole, R., Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 16, no. 9, pp. 1624-9, 2008.
D. S. Youngblood, Hatlevig, S. A., Hassinger, J. N., Iversen, P. L., and Moulton, H., Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells., Bioconjugate chemistry, vol. 18, no. 1, pp. 50-60, 2007.
S. Svasti, Suwanmanee, T., Fucharoen, S., Moulton, H., Nelson, M. H., Maeda, N., Smithies, O., and Kole, R., RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice., Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 4, pp. 1205-10, 2009.
A. Amantana, Moulton, H., Cate, M. L., Reddy, M. T., Whitehead, T., Hassinger, J. N., Youngblood, D. S., and Iversen, P. L., Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate., Bioconjugate chemistry, vol. 18, no. 4, pp. 1325-31, 2007.
H. Moulton, Wu, B., Jearawiriyapaisarn, N., Sazani, P., Lu, Q. Long, and Kole, R., Peptide-morpholino conjugate: a promising therapeutic for Duchenne muscular dystrophy., Annals of the New York Academy of Sciences, vol. 1175, pp. 55-60, 2009.
S. Abes, Moulton, H., Turner, J., Clair, P., Richard, J. P., Iversen, P., Gait, M. J., and Lebleu, B., Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides., Biochemical Society transactions, vol. 35, no. Pt 1, pp. 53-5, 2007.
H. Moulton and Moulton, J. D., Peptide-assisted delivery of steric-blocking antisense oligomers., Current opinion in molecular therapeutics, vol. 5, no. 2, pp. 123-32, 2003.
N. Ran, Lin, C., Leng, L., Han, G., Geng, M., Wu, Y., Bittner, S., Moulton, H., and Yin, H., MOTS-c promotes phosphorodiamidate morpholino oligomer uptake and efficacy in dystrophic mice., EMBO Mol Med, vol. 13, no. 2, p. e12993, 2021.
H. Moulton and Moulton, J. D., Morpholinos and their peptide conjugates: therapeutic promise and challenge for Duchenne muscular dystrophy., Biochim Biophys Acta, vol. 1798, no. 12, pp. 2296-303, 2010.
H. Moulton and Moulton, J. D., Morpholinos and their peptide conjugates: therapeutic promise and challenge for Duchenne muscular dystrophy., Biochimica et biophysica acta, vol. 1798, no. 12, pp. 2296-303, 2010.
S. Fletcher, Honeyman, K., Fall, A. M., Harding, P. L., Johnsen, R. D., Steinhaus, J. P., Moulton, H., Iversen, P. L., and Wilton, S. D., Morpholino oligomer-mediated exon skipping averts the onset of dystrophic pathology in the mdx mouse., Molecular therapy : the journal of the American Society of Gene Therapy, vol. 15, no. 9, pp. 1587-92, 2007.
P. L. Iversen, Mourich, D. V., and Moulton, H., Monoclonal antibodies to two epitopes of beta-human chorionic gonadotropin for the treatment of cancer., Current opinion in molecular therapeutics, vol. 5, no. 2, pp. 156-60, 2003.
S. Tripathi, Pohl, M. O., Zhou, Y., Rodriguez-Frandsen, A., Wang, G., Stein, D. A., Moulton, H., DeJesus, P., Che, J., Mulder, L. C. F., Yángüez, E., Andenmatten, D., Pache, L., Manicassamy, B., Albrecht, R. A., Gonzalez, M. G., Nguyen, Q., Brass, A., Elledge, S., White, M., Shapira, S., Hacohen, N., Karlas, A., Meyer, T. F., Shales, M., Gatorano, A., Johnson, J. R., Jang, G., Johnson, T., Verschueren, E., Sanders, D., Krogan, N., Shaw, M., König, R., Stertz, S., García-Sastre, A., and Chanda, S. K., Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding., Cell Host Microbe, vol. 18, no. 6, pp. 723-35, 2015.
B. Wu, Lu, P., Cloer, C., Shaban, M., Grewal, S., Milazi, S., Shah, S. N., Moulton, H., and Lu, Q. Long, Long-term rescue of dystrophin expression and improvement in muscle pathology and function in dystrophic mdx mice by peptide-conjugated morpholino., The American journal of pathology, vol. 181, no. 2, pp. 392-400, 2012.
B. Wu, Lu, P., Cloer, C., Shaban, M., Grewal, S., Milazi, S., Shah, S. N., Moulton, H., and Lu, Q. Long, Long-term rescue of dystrophin expression and improvement in muscle pathology and function in dystrophic mdx mice by peptide-conjugated morpholino., Am J Pathol, vol. 181, no. 2, pp. 392-400, 2012.
N. Jearawiriyapaisarn, Moulton, H., Sazani, P., Kole, R., and Willis, M. S., Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers., Cardiovascular research, vol. 85, no. 3, pp. 444-53, 2010.
N. Jearawiriyapaisarn, Moulton, H., Sazani, P., Kole, R., and Willis, M. S., Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers., Cardiovasc Res, vol. 85, no. 3, pp. 444-53, 2010.

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