Found 24 results
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Journal Article
L. E. Shorey, Castro, D. J., Baird, W. M., Siddens, L. K., Löhr, C. V., Matzke, M. M., Waters, K. M., Corley, R. A., and Williams, D. E., Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): timing of maternal exposures determines target tissue response in offspring., Cancer letters, vol. 317, no. 1, pp. 49-55, 2012.
L. M. Beaver, Buchanan, A., Sokolowski, E. I., Riscoe, A. N., Wong, C. P., Chang, J. H., Löhr, C. V., Williams, D. E., Dashwood, R. H., and Ho, E., Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention., Mol Nutr Food Res, vol. 58, no. 10, pp. 2001-13, 2014.
R. Wang, Kang, Y., Löhr, C. V., Fischer, K. A., C Bradford, S., Johnson, G., Dashwood, W. Mohaiza, Williams, D. E., Ho, E., and Dashwood, R. H., Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer., Cancer Lett, vol. 381, no. 2, pp. 341-8, 2016.
R. Wang, W Dashwood, M., Löhr, C. V., Fischer, K. A., Pereira, C. B., Louderback, M., Nakagama, H., Bailey, G. S., Williams, D. E., and Dashwood, R. H., Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat., Carcinogenesis, vol. 29, no. 4, pp. 834-9, 2008.
L. K. Siddens, Larkin, A., Krueger, S. K., Bradfield, C. A., Waters, K. M., Tilton, S. C., Pereira, C. B., Löhr, C. V., Arlt, V. M., Phillips, D. H., Williams, D. E., and Baird, W. M., Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse., Toxicology and applied pharmacology, vol. 264, no. 3, pp. 377-86, 2012.
P. Rajendran, Dashwood, W. - M., Li, L., Kang, Y., Kim, E., Johnson, G., Fischer, K. A., Löhr, C. V., Williams, D. E., Ho, E., Yamamoto, M., Lieberman, D. A., and Dashwood, R. H., Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon., Clin Epigenetics, vol. 7, p. 102, 2015.
Y. - S. Chen, Wang, R., Dashwood, W. - M., Löhr, C. V., Williams, D. E., Ho, E., Mertens-Talcott, S., and Dashwood, R. H., A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat., Arch Toxicol, vol. 91, no. 10, pp. 3415-3425, 2017.
S. C. Tilton, Siddens, L. K., Krueger, S. K., Larkin, A. J., Löhr, C. V., Williams, D. E., Baird, W. M., and Waters, K. M., Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential., Toxicol Sci, vol. 146, no. 1, pp. 135-45, 2015.
D. J. Castro, Löhr, C. V., Fischer, K. A., Pereira, C. B., and Williams, D. E., Lymphoma and lung cancer in offspring born to pregnant mice dosed with dibenzo[a,l]pyrene: the importance of in utero vs. lactational exposure., Toxicology and applied pharmacology, vol. 233, no. 3, pp. 454-8, 2008.
L. M. Beaver, Kuintzle, R., Buchanan, A., Wiley, M. W., Glasser, S. T., Wong, C. P., Johnson, G. S., Chang, J. H., Löhr, C. V., Williams, D. E., Dashwood, R. H., Hendrix, D. A., and Ho, E., Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer., J Nutr Biochem, vol. 42, pp. 72-83, 2017.
Z. Yu, Mahadevan, B., Löhr, C. V., Fischer, K. A., Louderback, M. A., Krueger, S. K., Pereira, C. B., Albershardt, D. J., Baird, W. M., Bailey, G. S., and Williams, D. E., Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene., Carcinogenesis, vol. 27, no. 10, pp. 2116-23, 2006.
D. J. Castro, Löhr, C. V., Fischer, K. A., Waters, K. M., Webb-Robertson, B. - J. M., Dashwood, R. H., Bailey, G. S., and Williams, D. E., Identifying efficacious approaches to chemoprevention with chlorophyllin, purified chlorophylls and freeze-dried spinach in a mouse model of transplacental carcinogenesis., Carcinogenesis, vol. 30, no. 2, pp. 315-20, 2009.
E. Kim, Bisson, W. H., Löhr, C. V., Williams, D. E., Ho, E., Dashwood, R. H., and Rajendran, P., Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors., Curr Top Med Chem, vol. 16, no. 7, pp. 714-31, 2016.
P. Rajendran, Kidane, A. I., Yu, T. - W., Dashwood, W. - M., Bisson, W. H., Löhr, C. V., Ho, E., Williams, D. E., and Dashwood, R. H., HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates., Epigenetics, vol. 8, no. 6, pp. 612-23, 2013.
D. J. Castro, Baird, W. M., Pereira, C. B., Giovanini, J., Löhr, C. V., Fischer, K. A., Yu, Z., Gonzalez, F. J., Krueger, S. K., and Williams, D. E., Fetal mouse Cyp1b1 and transplacental carcinogenesis from maternal exposure to dibenzo(a,l)pyrene., Cancer prevention research (Philadelphia, Pa.), vol. 1, no. 2, pp. 128-34, 2008.
R. Wang, Löhr, C. V., Fischer, K. A., W Dashwood, M., Greenwood, J. A., Ho, E., Williams, D. E., Ashktorab, H., Dashwood, M. R., and Dashwood, R. H., Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer., Int J Cancer, vol. 132, no. 5, pp. 1004-12, 2013.
R. Wang, Chen, Y. - S., Dashwood, W. - M., Li, Q., Löhr, C. V., Fischer, K. A., Ho, E., Williams, D. E., and Dashwood, R. H., Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors., Mol Carcinog, vol. 56, no. 7, pp. 1733-1742, 2017.
L. E. Shorey, Madeen, E. P., Atwell, L. L., Ho, E., Löhr, C. V., Pereira, C. B., Dashwood, R. H., and Williams, D. E., Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane., Toxicol Appl Pharmacol, vol. 270, no. 1, pp. 60-9, 2013.
E. P. Madeen, Löhr, C. V., You, H., Siddens, L. K., Krueger, S. K., Dashwood, R. H., Gonzalez, F. J., Baird, W. M., Ho, E., Bramer, L., Waters, K. M., and Williams, D. E., Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice., Mol Carcinog, vol. 56, no. 1, pp. 163-171, 2017.
L. K. Siddens, Bunde, K. L., Harper, T. A., McQuistan, T. J., Löhr, C. V., Bramer, L. M., Waters, K. M., Tilton, S. C., Krueger, S. K., Williams, D. E., and Baird, W. M., Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse., Toxicol Appl Pharmacol, vol. 287, no. 2, pp. 149-160, 2015.
O. Carter, Dashwood, R. H., Wang, R., W Dashwood, M., Orner, G. A., Fischer, K. A., Löhr, C. V., Pereira, C. B., Bailey, G. S., and Williams, D. E., Comparison of white tea, green tea, epigallocatechin-3-gallate, and caffeine as inhibitors of PhIP-induced colonic aberrant crypts., Nutrition and cancer, vol. 58, no. 1, pp. 60-5, 2007.
D. J. Castro, Yu, Z., Löhr, C. V., Pereira, C. B., Giovanini, J. N., Fischer, K. A., Orner, G. A., Dashwood, R. H., and Williams, D. E., Chemoprevention of dibenzo[a,l]pyrene transplacental carcinogenesis in mice born to mothers administered green tea: primary role of caffeine., Carcinogenesis, vol. 29, no. 8, pp. 1581-6, 2008.
R. Wang, W Dashwood, M., Löhr, C. V., Fischer, K. A., Nakagama, H., Williams, D. E., and Dashwood, R. H., beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet., Cancer science, vol. 99, no. 9, pp. 1754-9, 2008.
L. L. Atwell, Hsu, A., Wong, C. P., Stevens, J. F., Bella, D., Yu, T. - W., Pereira, C. B., Löhr, C. V., Christensen, J. Mark, Dashwood, R. H., Williams, D. E., Shannon, J., and Ho, E., Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract., Mol Nutr Food Res, vol. 59, no. 3, pp. 424-33, 2015.