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Home
Publications
Found 100 results
Author
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Type
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Hong M Moulton
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2021
M. Bersani
,
Rizzuti, M.
,
Pagliari, E.
,
Garbellini, M.
,
Saccomanno, D.
,
Moulton, H. M.
,
Bresolin, N.
,
Comi, G. P.
,
Corti, S.
, and
Nizzardo, M.
,
“
Cell-penetrating peptide-conjugated Morpholino rescues SMA in a symptomatic preclinical model.
”
,
Mol Ther
, 2021.
G. Green
,
Johnson, S. M.
,
Costello, H.
,
Brakel, K.
,
Harder, O.
,
Oomens, A. G.
,
Peeples, M. E.
,
Moulton, H. M.
, and
Niewiesk, S.
,
“
CX3CR1 Is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats.
”
,
J Virol
, vol. 95, no. 16, p. e0001021, 2021.
Y. Dang
,
van Heusden, C.
,
Nickerson, V.
,
Chung, F.
,
Wang, Y.
,
Quinney, N. L.
,
Gentzsch, M.
,
Randell, S. H.
,
Moulton, H. M.
,
Kole, R.
,
Ni, A.
,
Juliano, R. L.
, and
Kreda, S. M.
,
“
Enhanced delivery of peptide-morpholino oligonucleotides with a small molecule to correct splicing defects in the lung.
”
,
Nucleic Acids Res
, vol. 49, no. 11, pp. 6100-6113, 2021.
Y. Echigoya
,
Trieu, N.
,
Duddy, W.
,
Moulton, H. M.
,
Yin, H.
,
Partridge, T. A.
,
Hoffman, E. P.
,
Kornegay, J. N.
,
Rohret, F. A.
,
Rogers, C. S.
, and
Yokota, T.
,
“
A Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping.
”
,
Int J Mol Sci
, vol. 22, no. 23, 2021.
D. Bestle
,
Limburg, H.
,
Kruhl, D.
,
Harbig, A.
,
Stein, D. A.
,
Moulton, H. M.
,
Matrosovich, M.
,
Abdelwhab, E. M.
,
Stech, J.
, and
Böttcher-Friebertshäuser, E.
,
“
Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells.
”
,
J Virol
, vol. 95, no. 20, p. e0090621, 2021.
K. Rosenke
,
Leventhal, S.
,
Moulton, H. M.
,
Hatlevig, S.
,
Hawman, D.
,
Feldmann, H.
, and
Stein, D. A.
,
“
Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers.
”
,
J Antimicrob Chemother
, vol. 76, no. 2, pp. 413-417, 2021.
N. Ran
,
Lin, C.
,
Leng, L.
,
Han, G.
,
Geng, M.
,
Wu, Y.
,
Bittner, S.
,
Moulton, H. M.
, and
Yin, H.
,
“
MOTS-c promotes phosphorodiamidate morpholino oligomer uptake and efficacy in dystrophic mice.
”
,
EMBO Mol Med
, vol. 13, no. 2, p. e12993, 2021.
L. Martin-Sancho
,
Tripathi, S.
,
Rodriguez-Frandsen, A.
,
Pache, L.
,
Sanchez-Aparicio, M.
,
McGregor, M. J.
,
Haas, K. M.
,
Swaney, D. L.
,
Nguyen, T. T.
,
Mamede, J. I.
,
Churas, C.
,
Pratt, D.
,
Rosenthal, S. B.
,
Riva, L.
,
Nguyen, C.
,
Beltran-Raygoza, N.
,
Soonthornvacharin, S.
,
Wang, G.
,
Jimenez-Morales, D.
,
De Jesus, P. D.
,
Moulton, H. M.
,
Stein, D. A.
,
Chang, M. W.
,
Benner, C.
,
Ideker, T.
,
Albrecht, R. A.
,
Hultquist, J. F.
,
Krogan, N. J.
,
García-Sastre, A.
, and
Chanda, S. K.
,
“
Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy.
”
,
Nat Microbiol
, vol. 6, no. 10, pp. 1319-1333, 2021.
2020
M. McPhillie
,
Zhou, Y.
,
Bissati, K. El
,
Dubey, J.
,
Lorenzi, H.
,
Capper, M.
,
Lukens, A. K.
,
Hickman, M.
,
Muench, S.
,
Verma, S. Kumar
,
Weber, C. R.
,
Wheeler, K.
,
Gordon, J.
,
Sanders, J.
,
Moulton, H. M.
,
Wang, K.
,
Kim, T. - K.
,
He, Y.
,
Santos, T.
,
Woods, S.
,
Lee, P.
,
Donkin, D.
,
Kim, E.
,
Fraczek, L.
,
Lykins, J.
,
Esaa, F.
,
Alibana-Clouser, F.
,
Dovgin, S.
,
Weiss, L.
,
Brasseur, G.
,
Wirth, D.
,
Kent, M. L.
,
Hood, L.
,
Meunieur, B.
,
Roberts, C. W.
,
S Hasnain, S.
,
Antonyuk, S. V.
,
Fishwick, C.
, and
McLeod, R.
,
“
Author Correction: New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.
”
,
Sci Rep
, vol. 10, no. 1, p. 5512, 2020.
H. Yin
,
Boisguerin, P.
,
Moulton, H. M.
,
Betts, C.
,
Seow, Y.
,
Boutilier, J.
,
Wang, Q.
,
Walsh, A.
,
Lebleu, B.
, and
Wood, M. J. A.
,
“
Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency.
”
,
Mol Ther Nucleic Acids
, vol. 22, p. 166, 2020.
X. Gao
,
Zhao, J.
,
Han, G.
,
Zhang, Y.
,
Dong, X.
,
Cao, L.
,
Wang, Q.
,
Moulton, H. M.
, and
Yin, H.
,
“
Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide-Morpholino Conjugate in Dystrophin-Deficient mdx Mice.
”
,
Mol Ther
, vol. 28, no. 10, pp. 2299-2301, 2020.
L. Cao
,
Han, G.
,
Lin, C.
,
Gu, B.
,
Gao, X.
,
Moulton, H. M.
,
Seow, Y.
, and
Yin, H.
,
“
Erratum: Fructose Promotes Uptake and Activity of Oligonucleotides with Different Chemistries in a Context-Dependent Manner in Mice.
”
,
Mol Ther Nucleic Acids
, vol. 22, pp. 1040-1042, 2020.
H. Yin
,
Moulton, H. M.
,
Betts, C.
,
Merritt, T.
,
Seow, Y.
,
Ashraf, S.
,
Wang, Q.
,
Boutilier, J.
, and
Wood, M. J. A.
,
“
Functional Rescue of Dystrophin-Deficient mdx Mice by a Chimeric Peptide-PMO.
”
,
Mol Ther
, vol. 28, no. 10, pp. 2297-2298, 2020.
K. Rosenke
,
Leventhal, S.
,
Moulton, H. M.
,
Hatlevig, S.
,
Hawman, D.
,
Feldmann, H.
, and
Stein, D. A.
,
“
Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomers.
”
,
bioRxiv
, 2020.
D. Bestle
,
Heindl, M. Ruth
,
Limburg, H.
,
van, T. Van Lam
,
Pilgram, O.
,
Moulton, H. M.
,
Stein, D. A.
,
Hardes, K.
,
Eickmann, M.
,
Dolnik, O.
,
Rohde, C.
,
Klenk, H. - D.
,
Garten, W.
,
Steinmetzer, T.
, and
Böttcher-Friebertshäuser, E.
,
“
TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells.
”
,
Life Sci Alliance
, vol. 3, no. 9, 2020.
2019
L. Louis Seifert
,
Si, C.
,
Saha, D.
,
Sadic, M.
,
de Vries, M.
,
Ballentine, S.
,
Briley, A.
,
Wang, G.
,
Valero-Jimenez, A. M.
,
Mohamed, A.
,
Schaefer, U.
,
Moulton, H. M.
,
García-Sastre, A.
,
Tripathi, S.
,
Rosenberg, B. R.
, and
Dittmann, M.
,
“
The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response.
”
,
PLoS Pathog
, vol. 15, no. 11, p. e1007634, 2019.
H. Yin
,
Moulton, H. M.
,
Betts, C.
,
Seow, Y.
,
Boutilier, J.
,
Iverson, P. L.
, and
Wood, M. J. A.
,
“
A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.
”
,
Hum Mol Genet
, vol. 28, no. 4, p. 699, 2019.
G. Han
,
Gu, B.
,
Lin, C.
,
Ning, H.
,
Song, J.
,
Gao, X.
,
Moulton, H. M.
, and
Yin, H.
,
“
Hexose Potentiates Peptide-Conjugated Morpholino Oligomer Efficacy in Cardiac Muscles of Dystrophic Mice in an Age-Dependent Manner.
”
,
Mol Ther Nucleic Acids
, vol. 18, pp. 341-350, 2019.
H. Limburg
,
Harbig, A.
,
Bestle, D.
,
Stein, D. A.
,
Moulton, H. M.
,
Jaeger, J.
,
Janga, H.
,
Hardes, K.
,
Koepke, J.
,
Schulte, L.
,
Koczulla, A. Rembert
,
Schmeck, B.
,
Klenk, H. - D.
, and
Böttcher-Friebertshäuser, E.
,
“
TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes.
”
,
J Virol
, vol. 93, no. 21, 2019.
2018
X. Gao
,
Ran, N.
,
Dong, X.
,
Zuo, B.
,
Yang, R.
,
Zhou, Q.
,
Moulton, H. M.
,
Seow, Y.
, and
Yin, H.
,
“
Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy.
”
,
Sci Transl Med
, vol. 10, no. 444, 2018.
J. D. Lykins
,
Filippova, E. V.
,
Halavaty, A. S.
,
Minasov, G.
,
Zhou, Y.
,
Dubrovska, I.
,
Flores, K. J.
,
Shuvalova, L. A.
,
Ruan, J.
,
Bissati, K. El
,
Dovgin, S.
,
Roberts, C. W.
,
Woods, S.
,
Moulton, J. D.
,
Moulton, H. M.
,
McPhillie, M. J.
,
Muench, S. P.
,
Fishwick, C. W. G.
,
Sabini, E.
,
Shanmugam, D.
,
Roos, D. S.
,
McLeod, R.
,
Anderson, W. F.
, and
Ngô, H. M.
,
“
CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in .
”
,
Front Cell Infect Microbiol
, vol. 8, p. 352, 2018.
J. Kim
,
Clark, K.
,
Barton, C.
,
Tanguay, R.
, and
Moulton, H. M.
,
“
A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers.
”
,
Methods Mol Biol
, vol. 1828, pp. 293-306, 2018.
2017
G. Chow
,
Morcos, P. A.
, and
Moulton, H. M.
,
“
Aggregation and Disaggregation of Morpholino Oligomers in Solution.
”
,
Methods Mol Biol
, vol. 1565, pp. 31-38, 2017.
Y. Echigoya
,
Nakamura, A.
,
Nagata, T.
,
Urasawa, N.
,
Lim, K. Rowel Q.
,
Trieu, N.
,
Panesar, D.
,
Kuraoka, M.
,
Moulton, H. M.
,
Saito, T.
,
Aoki, Y.
,
Iversen, P.
,
Sazani, P.
,
Kole, R.
,
Maruyama, R.
,
Partridge, T.
,
Takeda, S. 'ichi
, and
Yokota, T.
,
“
Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy.
”
,
Proc Natl Acad Sci U S A
, vol. 114, no. 16, pp. 4213-4218, 2017.
H. M. Moulton
and
JD, M.
,
Morpholino Oligomers: Methods and Protocols. Methods in Molecular Biology
. Humana Press, 2017.
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