Found 24 results
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2021
Y. Echigoya, Trieu, N., Duddy, W., Moulton, H. M., Yin, H., Partridge, T. A., Hoffman, E. P., Kornegay, J. N., Rohret, F. A., Rogers, C. S., and Yokota, T., “A Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping.”, Int J Mol Sci, vol. 22, no. 23, 2021.
N. Ran, Lin, C., Leng, L., Han, G., Geng, M., Wu, Y., Bittner, S., Moulton, H. M., and Yin, H., “MOTS-c promotes phosphorodiamidate morpholino oligomer uptake and efficacy in dystrophic mice.”, EMBO Mol Med, vol. 13, no. 2, p. e12993, 2021.
2020
H. Yin, Boisguerin, P., Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Wang, Q., Walsh, A., Lebleu, B., and Wood, M. J. A., “Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency.”, Mol Ther Nucleic Acids, vol. 22, p. 166, 2020.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H. M., and Yin, H., “Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide-Morpholino Conjugate in Dystrophin-Deficient mdx Mice.”, Mol Ther, vol. 28, no. 10, pp. 2299-2301, 2020.
L. Cao, Han, G., Lin, C., Gu, B., Gao, X., Moulton, H. M., Seow, Y., and Yin, H., “Erratum: Fructose Promotes Uptake and Activity of Oligonucleotides with Different Chemistries in a Context-Dependent Manner in Mice.”, Mol Ther Nucleic Acids, vol. 22, pp. 1040-1042, 2020.
H. Yin, Moulton, H. M., Betts, C., Merritt, T., Seow, Y., Ashraf, S., Wang, Q., Boutilier, J., and Wood, M. J. A., “Functional Rescue of Dystrophin-Deficient mdx Mice by a Chimeric Peptide-PMO.”, Mol Ther, vol. 28, no. 10, pp. 2297-2298, 2020.
2019
H. Yin, Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Iverson, P. L., and Wood, M. J. A., “A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.”, Hum Mol Genet, vol. 28, no. 4, p. 699, 2019.
G. Han, Gu, B., Lin, C., Ning, H., Song, J., Gao, X., Moulton, H. M., and Yin, H., “Hexose Potentiates Peptide-Conjugated Morpholino Oligomer Efficacy in Cardiac Muscles of Dystrophic Mice in an Age-Dependent Manner.”, Mol Ther Nucleic Acids, vol. 18, pp. 341-350, 2019.
2018
X. Gao, Ran, N., Dong, X., Zuo, B., Yang, R., Zhou, Q., Moulton, H. M., Seow, Y., and Yin, H., “Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy.”, Sci Transl Med, vol. 10, no. 444, 2018.
2016
L. Cao, Han, G., Lin, C., Gu, B., Gao, X., Moulton, H. M., Seow, Y., and Yin, H., “Fructose Promotes Uptake and Activity of Oligonucleotides With Different Chemistries in a Context-dependent Manner in mdx Mice.”, Mol Ther Nucleic Acids, vol. 5, no. 6, p. e329, 2016.
2014
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H. M., and Yin, H., “Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice.”, Molecular therapy : the journal of the American Society of Gene Therapy, vol. 22, no. 7, pp. 1333-41, 2014.
X. Gao, Zhao, J., Han, G., Zhang, Y., Dong, X., Cao, L., Wang, Q., Moulton, H. M., and Yin, H., “Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice.”, Mol Ther, vol. 22, no. 7, pp. 1333-1341, 2014.
2013
H. Yin, Boisguerin, P., Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Wang, Q., Walsh, A., Lebleu, B., and Wood, M. Ja, “Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency.”, Mol Ther Nucleic Acids, vol. 2, p. e124, 2013.
H. Yin, Boisguerin, P., Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Wang, Q., Walsh, A., Lebleu, B., and Wood, M. J. A., “Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency.”, Molecular therapy. Nucleic acids, vol. 2, p. e124, 2013.
2011
H. Yin, Moulton, H. M., Betts, C., and Wood, M., “CPP-directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy.”, Methods in molecular biology (Clifton, N.J.), vol. 683, pp. 321-38, 2011.
H. Yin, Moulton, H. M., Betts, C., and Wood, M., “CPP-directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy.”, Methods Mol Biol, vol. 683, pp. 321-38, 2011.
A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H. M., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., “Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.”, Human molecular genetics, vol. 20, no. 3, pp. 413-21, 2011.
A. Crisp, Yin, H., Goyenvalle, A., Betts, C., Moulton, H. M., Seow, Y., Babbs, A., Merritt, T., Saleh, A. F., Gait, M. J., Stuckey, D. J., Clarke, K., Davies, K. E., and Wood, M. J. A., “Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.”, Hum Mol Genet, vol. 20, no. 3, pp. 413-21, 2011.
2010
H. Yin, Moulton, H. M., Betts, C., Merritt, T., Seow, Y., Ashraf, S., Wang, Q., Boutilier, J., and Wood, M. J. A., “Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO.”, Molecular therapy : the journal of the American Society of Gene Therapy, vol. 18, no. 10, pp. 1822-9, 2010.
H. Yin, Moulton, H. M., Betts, C., Merritt, T., Seow, Y., Ashraf, S., Wang, Q., Boutilier, J., and Wood, M. Ja, “Functional rescue of dystrophin-deficient mdx mice by a chimeric peptide-PMO.”, Mol Ther, vol. 18, no. 10, pp. 1822-9, 2010.
Q. Wang, Yin, H., Camelliti, P., Betts, C., Moulton, H. M., Lee, H., Saleh, A. F., Gait, M. J., and Wood, M. J. A., “In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy.”, The journal of gene medicine, vol. 12, no. 4, pp. 354-64, 2010.
Q. Wang, Yin, H., Camelliti, P., Betts, C., Moulton, H. M., Lee, H., Saleh, A. F., Gait, M. J., and Wood, M. J. A., “In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy.”, J Gene Med, vol. 12, no. 4, pp. 354-64, 2010.
2009
H. Yin, Moulton, H. M., Betts, C., Seow, Y., Boutilier, J., Iverson, P. L., and Wood, M. J. A., “A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.”, Human molecular genetics, vol. 18, no. 22, pp. 4405-14, 2009.
2008
H. Yin, Moulton, H. M., Seow, Y., Boyd, C., Boutilier, J., Iverson, P., and Wood, M. J. A., “Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function.”, Human molecular genetics, vol. 17, no. 24, pp. 3909-18, 2008.