Häse Lab Research
Pathogenic species have to deal with a wide range of environments both within and outside the host and most have elaborate regulatory circuits to ensure the correct temporal and spatial expression of virulence factors. However, in most cases the primary clues used by the bacteria to determine whether they are in the host and the mechanisms by which this sensing occurs are not well understood. Vibrio cholerae is the causative agent of the potentially lethal epidemic diarrheal disease cholera.