Luiz E. Bermudez Mycobacterial pathogenesis and new therapies to mycobacterial infection. Mycobacterium tuberculosis, Mycobacterium avium, Mycobacterium abscessus and Mycobacterium avium subsp paratuberculosis. Infection of the human and animal host interaction with mucosal surface, survival mechanism in the host, biofilm and its role in disease. Macrophages, Natural Killer cells and T lymphocyte participation in host defense against mycobacterial infection.