Brian Dolan

Associate Professor, Immunology

Research in my lab is focused on two main areas. The first is the biology of antigen presentation, the process by which the cells of the body alert the adaptive immune system to the presence of intracellular pathogens, such as viruses, or oncogenic transformation. We are trying to determine which cellular pathways are necessary to successfully present the foreign peptide on major histocompatibility complex class I (MHC I) proteins at the cell surface, which serve to flag down disease specific cytotoxic T cells. We are also interested in studying immune responses in wild animal populations as it relates to disease spread.