- Future Students
- Current Students
- Faculty & Staff
Paraneoplastic thrombocytosis-induced systemic thromboembolism in a cat.
|Title||Paraneoplastic thrombocytosis-induced systemic thromboembolism in a cat.|
|Publication Type||Journal Article|
|Year of Publication||1999|
|Authors||Hogan DF, Dhaliwal RS, Sisson DD, Kitchell BE|
|Journal||Journal of the American Animal Hospital Association|
|Date Published||1999 Nov-Dec|
|Keywords||Animals, Aorta, Thoracic, Bone Marrow, Cat Diseases, Cats, Diagnosis, Differential, Euthanasia, Fatal Outcome, Lung, Lung Neoplasms, Male, Paraneoplastic Syndromes, Thrombocytosis, Thromboembolism|
A six-year-old cat presented with clinical signs consistent with distal aortic thromboembolism while clinical signs of cardiovascular disease were absent. Diagnostics, including thoracic radiographs, electrocardiography, and echocardiography revealed no cardiovascular anomalies. Thoracic radiographs revealed multifocal pulmonary lesions consistent with neoplasia. Complete blood cell count demonstrated a marked thrombocytosis, leukopenia, and neutropenia. Histopathology of the pulmonary lesions confirmed multiple bronchoalveolar carcinomas. Myelodysplasia with megakaryocytic hyperplasia and ineffective myelopoiesis was noted on bone-marrow histopathology from multiple sites. The absence of other causes suggested a paraneoplastic thrombocytosis. The diagnosis of paraneoplastic thrombocytosis-induced thromboembolism was made due to the lack of underlying cardiac disease and the presence of a marked thrombocytosis. The presence of thrombocytosis and thromboembolism associated with neoplasia is discussed.
|Alternate Journal||J Am Anim Hosp Assoc|