Title | Cellular and molecular mechanisms of internalization of mycobacteria by host cells. |
Publication Type | Journal Article |
Year of Publication | 2001 |
Authors | Bermudez, LE, Sangari, FJ |
Journal | Microbes and infection / Institut Pasteur |
Volume | 3 |
Issue | 1 |
Pagination | 37-42 |
Date Published | 2001 Jan |
Keywords | Schwann Cells |
Abstract | Mycobacteria are intracellular pathogens capable of invading mononuclear phagocytes, mucosal epithelial cells (including M cells) and Schwann cells. To enter cells, mycobacteria have been shown to interact with several molecules on macrophage and epithelial cell surfaces. This suggests adaptation to the host environment. In this review we address the strategies used by pathogenic mycobacteria to gain access to the intracellular environment. |