TitleChlamydia trachomatis IncA is localized to the inclusion membrane and is recognized by antisera from infected humans and primates.
Publication TypeJournal Article
Year of Publication1998
AuthorsBannantine, JP, Stamm, WE, Suchland, RJ, Rockey, DD
JournalInfect Immun
Volume66
Issue12
Pagination6017-21
Date Published1998 Dec
ISSN0019-9567
KeywordsAnimals, Antibodies, Bacterial, Bacterial Proteins, Cell Compartmentation, Chlamydia Infections, Chlamydia trachomatis, Chlamydophila psittaci, Humans, Macaca fascicularis, Membrane Proteins, Phosphoproteins, Sequence Homology, Amino Acid, Species Specificity
Abstract

Chlamydia psittaci produces a collection of proteins, termed IncA, IncB, and IncC, that are localized to the chlamydial inclusion membrane. In this report we demonstrate that IncA is also produced by Chlamydia trachomatis. C. trachomatis IncA is structurally similar to C. psittaci IncA and is also localized to the inclusion membrane. Immunoblot analysis demonstrated that sera from C. trachomatis-infected patients and from experimentally infected monkeys both recognized C. trachomatis IncA.
DOI10.1128/IAI.66.12.6017-6021.1998
Alternate JournalInfect Immun
PubMed ID9826388
PubMed Central IDPMC108764
Grant ListN01AI75329 / AI / NIAID NIH HHS / United States
U19 AI031448 / AI / NIAID NIH HHS / United States
AI-31448 / AI / NIAID NIH HHS / United States
AI-42869-01 / AI / NIAID NIH HHS / United States