TitleComplete genome sequence and annotation of the Treponema pallidum subsp. pallidum Chicago strain.
Publication TypeJournal Article
Year of Publication2010
AuthorsGiacani, L, Jeffrey, BM, Molini, BJ, Le, HVT, Lukehart, SA, Centurion-Lara, A, Rockey, DD
JournalJournal of bacteriology
Date Published2010 May
KeywordsTreponema pallidum

In syphilis research, the Nichols strain of Treponema pallidum, isolated in 1912, has been the most widely studied. Recently, important differences among T. pallidum strains emerged; therefore, we sequenced and annotated the Chicago strain genome to facilitate and encourage the use of this strain in studying the pathogenesis of syphilis.